Influenza Nucleoprotein 抗体 (Influenza A Virus)
Quick Overview for Influenza Nucleoprotein 抗体 (Influenza A Virus) (ABIN2754714)
抗原
See all Influenza Nucleoprotein (NP) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Caprylic Acid Ammonium Sulfate Precipitation purified
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免疫原
- Recombinant Influenza A virus Nucleoprotein protein
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亚型
- IgG
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anti-Influenza Nucleoprotein antibody (Influenza A Virus H2N2) (H1N1), (H2N2), (H3N2), (H5N1), (H5N2)
NP 适用: Influenza A Virus H2N2 ELISA, WB, IF, IHC, IP, IC 宿主: 小鼠 Monoclonal C43 unconjugated
anti-Influenza Nucleoprotein antibody (Influenza A Virus H2N2) (H1N1), (H2N2), (H3N2), (H5N1), (H5N2) (HRP)NP 适用: Influenza A Virus H2N2 ELISA, WB, IHC, IC 宿主: 小鼠 Monoclonal C43 HRP
anti-Influenza Nucleoprotein antibody (Influenza A Virus H2N2) (AA 2-498)NP 适用: Influenza A Virus H2N2 ELISA 宿主: 小鼠 Monoclonal 9C11 unconjugated
anti-Influenza Nucleoprotein antibody (Influenza B Virus (B/Lee/40))NP 适用: Influenza B Virus ELISA 宿主: 小鼠 Monoclonal 1A2A11 unconjugated
anti-Influenza Nucleoprotein antibody (Influenza A Virus H1N1)NP 适用: Influenza A Virus H1N1 ELISA, WB, PrA 宿主: 小鼠 Monoclonal B248M unconjugated
anti-Influenza Nucleoprotein antibody (Influenza A Virus H1N1)NP 适用: Influenza A Virus H1N1 ELISA, WB, PrA 宿主: 小鼠 Monoclonal B247M unconjugated
anti-Influenza Nucleoprotein antibody (Influenza B Virus)NP 适用: Influenza B Virus ELISA, WB, PrA 宿主: 小鼠 Monoclonal B267M unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C/-80 °C
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- Influenza Nucleoprotein (NP)
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别名
- Influenza Nucleoprotein
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物质类
- Influenza Protein
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背景
- Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
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UniProt
- P03466
抗原
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