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IL9 Receptor 抗体

There are 2+ publications for this product available. The 小鼠 单克隆 anti-IL9 Receptor antibody is suitable to detect IL9 Receptor in samples from 人. It has been validated for ELISA, FACS 和 Func.
产品编号 ABIN2749221
发货至: 中国
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Quick Overview for IL9 Receptor 抗体 (ABIN2749221)

抗原

See all IL9 Receptor (IL9R) 抗体
IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL9 Receptor antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS), Functional Studies (Func)

克隆位点

AH9R7
  • 原理

    Anti-Hu CD129 Purified Low Endotoxin

    特异性

    The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    内毒素水平

    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

    免疫原

    Human CD129-transfected cell line

    亚型

    IgG2b kappa
  • 应用备注

    Functional application: Blocking.
    Flow cytometry: It is recommended to use bright fluorochromes or signal multiplying detection.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Pilette, Ouadrhiri, Van Snick, Renauld, Staquet, Vaerman, Sibille: "Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9." in: The European respiratory journal, Vol. 20, Issue 5, pp. 1198-205, (2002) (PubMed).

    De Smedt, Verhasselt, Kerre, Vanhecke, Naessens, Leclercq, Renauld, Van Snick, Plum: "Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1761-7, (2000) (PubMed).

  • 抗原

    IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

    别名

    CD129

    背景

    Interleukin 9 receptor,CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.,IL9R

    基因ID

    3581

    UniProt

    Q01113

    途径

    JAK/STAT Signaling, Growth Factor Binding
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