Ki-67 抗体 (PE)
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北京 101111
Quick Overview for Ki-67 抗体 (PE) (ABIN2749194)
抗原
See all Ki-67 (MKI67) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-Ki-67 PE
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特异性
- The mouse monoclonal antibody Ki-67 recognizes Ki-67 antigen, a non-histone nuclear protein expressed exclusively in proliferating cells.
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交叉反应 （详细）
- Human, Bovine
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Nuclei of the Hodgkin lymphoma cell line L428
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亚型
- IgG1
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anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1201-1300) antibody
MKI67 适用: 人, 小鼠, 大鼠, 兔, 山羊 ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2293-2478) antibodyMKI67 适用: 人 IHC, WB, FACS, IF, StM 宿主: 小鼠 Monoclonal MKI67-2461 unconjugated
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2293-2478) antibodyMKI67 适用: 人 IHC, WB, FACS, IF, StM 宿主: 小鼠 Monoclonal MKI67-2462 unconjugated
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1160-1493) antibodyMKI67 适用: 人 IHC, WB, IHC (p) 宿主: 大鼠 Monoclonal 9C3 unconjugated
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2815-2928) antibodyMKI67 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1160-1493) antibodyMKI67 适用: 人 IHC, WB, FACS, ELISA 宿主: 小鼠 Monoclonal 7B12B1 unconjugated
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) antibodyMKI67 适用: 人, Cow IHC, WB, FACS, ICC 宿主: 小鼠 Polyclonal unconjugated
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2924-3256) antibodyMKI67 适用: 人 IHC, IHC (p) 宿主: 小鼠 Monoclonal 8H5 unconjugated
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 1160-1493) antibodyMKI67 适用: 人 IHC, IHC (p) 宿主: 大鼠 Monoclonal 5B10 unconjugated
anti-Antigen Identified By Monoclonal Antibody Ki-67 (MKI67) (AA 2860-3256) antibodyMKI67 适用: 人 IHC, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins." in: The Journal of cell biology, Vol. 123, Issue 3, pp. 513-22, (1993) (PubMed).
: "Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 133, Issue 4, pp. 1710-5, (1984) (PubMed).
: "Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation." in: International journal of cancer. Journal international du cancer, Vol. 31, Issue 1, pp. 13-20, (1983) (PubMed).
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: "The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins." in: The Journal of cell biology, Vol. 123, Issue 3, pp. 513-22, (1993) (PubMed).
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- Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
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别名
- Ki-67
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背景
- Marker of proliferation Ki-67,Ki-67 is a highly protease-sensitive nuclear protein expressed in two isoforms (345 kDa and 395 kDa), both of which are identified by the antibody clone Ki-67. The Ki-67 antigen is essential for cell proliferation and its expression is restricted to the cycling cells. It is detected in G1, S, G2 and M phase, whereas it is absent in cells which are in G0 phase and it is not associated with DNA repair processes. Ki-67 thus represents an important tool for detection of proliferating cells, which is of great importance in tumor diagnostics and is commonly used as a prognostic factor in cancer studies.,KIA, MIB, Marker of proliferation Ki67, MKI67
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基因ID
- 4288
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UniProt
- P46013
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途径
- Glycosaminoglycan Metabolic Process
抗原
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