Cadherin 5 抗体
(2 references)Quick Overview for Cadherin 5 抗体 (ABIN2749192)
抗原
See all Cadherin 5 (CDH5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD144 Purified
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特异性
- The mouse monoclonal antibody 55-7H1 recognizes a calcium-independent extracellular epitope on CD144 (VE-cadherin, cadherin 5), an adhesion molecule expressed on endothelial cells.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Human endothelial cells
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亚型
- IgG1 kappa
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anti-Cadherin 5 (CDH5) (AA 601-700) antibody
CDH5 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, ICC, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 68-307) antibodyCDH5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 650-750) antibodyCDH5 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 29-223) antibodyCDH5 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3D5C7 unconjugated
anti-Cadherin 5 (CDH5) (C-Term) antibodyCDH5 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 766-784) antibodyCDH5 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 251-320) antibodyCDH5 适用: 人, 小鼠 FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 59-382) antibodyCDH5 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 259-358) antibodyCDH5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) antibodyCDH5 适用: 人 WB, FACS, IF, Func, IA 宿主: 小鼠 Monoclonal BV9 unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Establishment of a human in vitro model of the outer blood-retinal barrier." in: Journal of anatomy, Vol. 211, Issue 6, pp. 707-16, (2007) (PubMed).
: "Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members." in: Blood, Vol. 105, Issue 8, pp. 3169-77, (2005) (PubMed).
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: "Establishment of a human in vitro model of the outer blood-retinal barrier." in: Journal of anatomy, Vol. 211, Issue 6, pp. 707-16, (2007) (PubMed).
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- Cadherin 5 (CDH5)
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别名
- CD144
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背景
- Cadherin 5,CD144 / VE-cadherin (cadherin 5) is the major cadherin that is present at endothelial junctions. It is also strictly endothelial specific. Under vascular permeability increasing conditions (and also in capillaries and veins) CD144 is being phosphorylated, which promotes its rapid and reversible internalization. On the contrary, binding of p120 catenin (delta1 catenin) maintains CD144 localization at the plasma membrane, which stabilizes the junction and reduces vascular permeability.,Cadherin 5, CDH5, 7B4, VE-cadherin
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基因ID
- 1003
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UniProt
- P33151
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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