CCR3 抗体 (PE)
(1 reference)Quick Overview for CCR3 抗体 (PE) (ABIN2749177)
抗原
See all CCR3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD193 PE
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特异性
- The mouse monoclonal antibody 5E8 recognizes an extracellular epitope of CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed above all in eosinophils and basophils.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- human CD193 transfectants
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亚型
- IgG2b kappa
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anti-Chemokine (C-C Motif) Receptor 3 (CCR3) antibody
CCR3 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 8E9H10 unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 251-355) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 306-355) antibodyCCR3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (AA 5-28) antibodyCCR3 适用: 人, 小鼠 WB, IHC, IHC (p), ICC 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (N-Term) antibodyCCR3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (C-Term) antibodyCCR3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (Extracellular Domain) antibodyCCR3 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 3 (CCR3) (N-Term) antibodyCCR3 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "NADPH oxidase-independent formation of extracellular DNA traps by basophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5314-23, (2014) (PubMed).
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: "NADPH oxidase-independent formation of extracellular DNA traps by basophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5314-23, (2014) (PubMed).
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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别名
- CD193
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背景
- C-C motif chemokine receptor 3,CD193 / CCR3 is a G-protein coupled receptor for several chemokines, namely CCL11 (eotaxin), CCL26 (eotaxin-3), CCL7 (MCP-4), or CCL5 (RANTES). It is highly expressed on eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. CD193 is the key eosinophil chemokine receptor responsible for regulation of eosinophil migration and function. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.,CCR3, CKR3, CMKBR3, CC-CKR-3
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基因ID
- 1232
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UniProt
- P51677
抗原
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