SLAMF1 抗体 (PE)
(2 references)Quick Overview for SLAMF1 抗体 (PE) (ABIN2749109)
抗原
See all SLAMF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD150 PE
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特异性
- The mouse monoclonal antibody SLAM.4 recognizes an extracellular epitope of CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Human CD150-transfected 300.19 cells
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亚型
- IgG1
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anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 19-236) antibody
SLAMF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (Tyr1096) antibodySLAMF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 231-335) antibodySLAMF1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 69-204) antibodySLAMF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibodySLAMF1 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal SLAM-4 unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibody (FITC)SLAMF1 适用: 人 FACS 宿主: 小鼠 Monoclonal SLAM-4 FITC
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (C-Term) antibodySLAMF1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibody (APC)SLAMF1 适用: 人 FACS 宿主: 小鼠 Monoclonal SLAM-4 APC
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 21-237) antibodySLAMF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibodySLAMF1 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 9D1 unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).
: "Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)." in: Tissue antigens, Vol. 64, Issue 2, pp. 132-44, (2004) (PubMed).
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: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).
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- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
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别名
- CD150
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背景
- Signaling lymphocytic activation molecule family m,CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.,SLAM, SLAMF1
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基因ID
- 6504
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UniProt
- Q13291
抗原
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