电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IL9 Receptor 抗体 (PE)

This anti-IL9 Receptor antibody is a 小鼠 单克隆 antibody detecting IL9 Receptor in FACS. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2749105
发货至: 中国

Quick Overview for IL9 Receptor 抗体 (PE) (ABIN2749105)

抗原

See all IL9 Receptor (IL9R) 抗体
IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

适用

  • 42
  • 20
  • 2

宿主

  • 33
  • 12
  • 2
小鼠

克隆类型

  • 31
  • 15
  • 1
单克隆

标记

  • 31
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL9 Receptor antibody is conjugated to PE

应用范围

  • 26
  • 25
  • 22
  • 10
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
Flow Cytometry (FACS)

克隆位点

AH9R7
  • 原理

    Anti-Hu CD129 PE

    特异性

    The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Human CD129-transfected cell line

    亚型

    IgG2b kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Pilette, Ouadrhiri, Van Snick, Renauld, Staquet, Vaerman, Sibille: "Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9." in: The European respiratory journal, Vol. 20, Issue 5, pp. 1198-205, (2002) (PubMed).

    Pilette, Ouadrhiri, Van Snick, Renauld, Staquet, Vaerman, Sibille: "IL-9 inhibits oxidative burst and TNF-alpha release in lipopolysaccharide-stimulated human monocytes through TGF-beta." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 8, pp. 4103-11, (2002) (PubMed).

    De Smedt, Verhasselt, Kerre, Vanhecke, Naessens, Leclercq, Renauld, Van Snick, Plum: "Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1761-7, (2000) (PubMed).

  • 抗原

    IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

    别名

    CD129

    背景

    Interleukin 9 receptor,CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.,IL9R

    基因ID

    3581

    UniProt

    Q01113

    途径

    JAK/STAT Signaling, Growth Factor Binding
You are here:
Chat with us!