IL9 Receptor 抗体 (PE)
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北京 101111
Quick Overview for IL9 Receptor 抗体 (PE) (ABIN2749105)
抗原
See all IL9 Receptor (IL9R) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD129 PE
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特异性
- The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Human CD129-transfected cell line
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亚型
- IgG2b kappa
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anti-Interleukin 9 Receptor (IL9R) (AA 41-270) antibody
IL9R 适用: 人, 大鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4A11H2 unconjugated
anti-Interleukin 9 Receptor (IL9R) (AA 41-270) antibodyIL9R 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1C2A6 unconjugated
anti-Interleukin 9 Receptor (IL9R) (AA 272-521) antibodyIL9R 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 9 Receptor (IL9R) (AA 47-257) antibodyIL9R 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 9 Receptor (IL9R) (AA 472-521), (pSer519) antibodyIL9R 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 9 Receptor (IL9R) (AA 50-150) antibodyIL9R 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 9 Receptor (IL9R) antibodyIL9R 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 9 Receptor (IL9R) antibodyIL9R 适用: 人 IP, BP 宿主: 兔 Chimeric AH9R2 unconjugated Recombinant Antibody
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9." in: The European respiratory journal, Vol. 20, Issue 5, pp. 1198-205, (2002) (PubMed).
: "IL-9 inhibits oxidative burst and TNF-alpha release in lipopolysaccharide-stimulated human monocytes through TGF-beta." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 8, pp. 4103-11, (2002) (PubMed).
: "Signals from the IL-9 receptor are critical for the early stages of human intrathymic T cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1761-7, (2000) (PubMed).
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: "Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9." in: The European respiratory journal, Vol. 20, Issue 5, pp. 1198-205, (2002) (PubMed).
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- IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))
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别名
- CD129
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背景
- Interleukin 9 receptor,CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.,IL9R
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基因ID
- 3581
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UniProt
- Q01113
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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