CD84 抗体
(4 references)-
- 抗原 See all CD84 抗体
- CD84
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD84 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- 特异性
- The mouse monoclonal antibody CD84.1.21 recognizes an extracellular epitope of CD84, a single chain cell surface glycoprotein of 64-82 kDa, predominantly expressed B cells, monocytes, platelets and some T cells.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 内毒素水平
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
- 免疫原
- CD84-transfected 300.19 cell line
- 克隆位点
- CD84-1-21
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CD84 Primary Antibody
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anti-CD84 (CD84) (Internal Region) antibody
CD84 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD84 (CD84) antibody (FITC)CD84 适用: 人 FACS 宿主: 小鼠 Monoclonal CD84-1-21 FITC
anti-CD84 (CD84) (AA 22-225) antibodyCD84 适用: 人 FACS, WB, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 5D12H10 unconjugated
anti-CD84 (CD84) (AA 22-225) antibodyCD84 适用: 人 FACS, WB, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 2D11D1 unconjugated
anti-CD84 (CD84) (AA 231-329) antibodyCD84 适用: 小鼠, 大鼠 FACS, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD84 (CD84) (AA 22-121) antibodyCD84 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G10 unconjugated
anti-CD84 (CD84) antibodyCD84 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal CD84-1-21 unconjugated
anti-CD84 (CD84) (AA 22-225) antibodyCD84 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD84 (CD84) antibodyCD84 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 152-1D5 unconjugated
anti-CD84 (CD84) (AA 1-328) antibodyCD84 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Functional application: Enhancement of CD3-induced IFN-gamma production.
Flow cytometry: Recommended dilution: 1-4 μg/mL - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).
: "Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells." in: The EMBO journal, Vol. 20, Issue 21, pp. 5840-52, (2001) (PubMed).
: "CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 7, pp. 3668-76, (2001) (PubMed).
: "Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP." in: Blood, Vol. 97, Issue 12, pp. 3867-74, (2001) (PubMed).
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: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).
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- 抗原
- CD84
- 别名
- CD84 (CD84 产品)
- 别名
- RGD1564553 antibody, A130013D22Rik antibody, CDw84 antibody, SLAMF5 antibody, LY9B antibody, hCD84 antibody, mCD84 antibody, CD84 molecule antibody, CD84 antigen antibody, Cd84 antibody, CD84 antibody
- 背景
- CD84 Molecule,CD84 is a highly glycosylated homophilic receptor of SLAM family. It is expressed on platelets and various types of leukocytes, especially following their activation. Ligation of CD84 leads to its phosphorylation on tyrosine residues within the cytoplasmic tail. These docking sites are recognized by downstream signaling molecules, such as phosphatase SHP-2 and adaptor protein SAP/SH2D1A. The function of CD84 has not been fully elucidated yet. Although predominantly activating receptor, its modulating activity was also demonstrated.,LY9B, SLAMF5
- 基因ID
- 8832
- UniProt
- Q9UIB8
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