CD84 抗体
(4 references)Quick Overview for CD84 抗体 (ABIN2749034)
抗原
See all CD84 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD84 Purified Low Endotoxin
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特异性
- The mouse monoclonal antibody CD84.1.21 recognizes an extracellular epitope of CD84, a single chain cell surface glycoprotein of 64-82 kDa, predominantly expressed B cells, monocytes, platelets and some T cells.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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内毒素水平
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
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免疫原
- CD84-transfected 300.19 cell line
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亚型
- IgG2a kappa
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anti-CD84 (CD84) (Internal Region) antibody
CD84 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD84 (CD84) antibody (FITC)CD84 适用: 人 FACS 宿主: 小鼠 Monoclonal CD84-1-21 FITC
anti-CD84 (CD84) (AA 22-225) antibodyCD84 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5D12H10 unconjugated
anti-CD84 (CD84) (AA 22-225) antibodyCD84 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5B9E10 unconjugated
anti-CD84 (CD84) (AA 231-329) antibodyCD84 适用: 小鼠, 大鼠 FACS, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD84 (CD84) (AA 32-222) antibodyCD84 适用: 小鼠 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD84 (CD84) (AA 22-121) antibodyCD84 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G10 unconjugated
anti-CD84 (CD84) antibodyCD84 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal CD84-1-21 unconjugated
anti-CD84 (CD84) (AA 22-225) antibodyCD84 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD84 (CD84) antibodyCD84 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 152-1D5 unconjugated
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应用备注
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Functional application: Enhancement of CD3-induced IFN-gamma production.
Flow cytometry: Recommended dilution: 1-4 μg/mL -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).
: "Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells." in: The EMBO journal, Vol. 20, Issue 21, pp. 5840-52, (2001) (PubMed).
: "CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 7, pp. 3668-76, (2001) (PubMed).
: "Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP." in: Blood, Vol. 97, Issue 12, pp. 3867-74, (2001) (PubMed).
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: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).
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- CD84
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别名
- CD84
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背景
- CD84 Molecule,CD84 is a highly glycosylated homophilic receptor of SLAM family. It is expressed on platelets and various types of leukocytes, especially following their activation. Ligation of CD84 leads to its phosphorylation on tyrosine residues within the cytoplasmic tail. These docking sites are recognized by downstream signaling molecules, such as phosphatase SHP-2 and adaptor protein SAP/SH2D1A. The function of CD84 has not been fully elucidated yet. Although predominantly activating receptor, its modulating activity was also demonstrated.,LY9B, SLAMF5
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基因ID
- 8832
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UniProt
- Q9UIB8
抗原
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