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PDE4A 抗体

This 兔 多克隆 antibody specifically detects PDE4A in WB, IHC, IF, ELISA, IP, ICC 和 CM. It exhibits reactivity toward 人, 小鼠, 大鼠, 小鸡 和 猴. It has been mentioned in 13+ publications
产品编号 ABIN2747099
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PDE4A 抗体 (ABIN2747099)

抗原

See all PDE4A 抗体
PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

适用

  • 54
  • 34
  • 26
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
人, 小鼠, 大鼠, 小鸡, 猴

宿主

  • 47
  • 7

克隆类型

  • 49
  • 5
多克隆

标记

  • 21
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PDE4A antibody is un-conjugated

应用范围

  • 45
  • 16
  • 14
  • 13
  • 12
  • 6
  • 6
  • 6
  • 5
  • 4
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Confocal Microscopy (CM)
  • 纯化方法

    Affinity Purified

    免疫原

    Synthetic peptide common to most PDE4 subtypes: PDE4A, PDE4D, PDE4B

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.62 μg/μL
  • Lee, Shin, Hong: "The Regulatory Role of Rolipram on Inflammatory Mediators and Cholinergic/Adrenergic Stimulation-Induced Signals in Isolated Primary Mouse Submandibular Gland Cells." in: Mediators of inflammation, Vol. 2016, pp. 3745961, (2017) (PubMed).

    Wang, Zhang, Liu, Zhao, Zhang, Yuan, An, Li, Wang, Qin, Wilson, ODonnell, Zhang, Li: "RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects." in: British journal of pharmacology, Vol. 168, Issue 4, pp. 1001-14, (2013) (PubMed).

    Castiglione, Bergamini, Russo, La Croce, Castagna, Colciago, Salonia, Rigatti, Montorsi, Hedlund: "Inhibition of phosphodiesterase 4 enhances clitoral and vaginal blood flow responses to dorsal clitoral nerve stimulation or PGE1 in anesthetized female rats." in: The journal of sexual medicine, Vol. 10, Issue 4, pp. 939-50, (2013) (PubMed).

    Muzaffar, Jeremy, Angelini, Shukla: "NADPH oxidase 4 mediates upregulation of type 4 phosphodiesterases in human endothelial cells." in: Journal of cellular physiology, Vol. 227, Issue 5, pp. 1941-50, (2012) (PubMed).

    Li, Cheng, Huang, Conti, Wilson, ODonnell, Zhang: "Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 1, pp. 172-83, (2011) (PubMed).

    Yagi, Tada, Kitazato, Tamura, Satomi, Nagahiro: "Ibudilast inhibits cerebral aneurysms by down-regulating inflammation-related molecules in the vascular wall of rats." in: Neurosurgery, Vol. 66, Issue 3, pp. 551-9; discussion 559, (2010) (PubMed).

    Dodd-o, Hristopoulos, Kibler, Gutkowska, Mukaddam-Daher, Gonzalez, Welsh-Servinsky, Pearse: "The role of natriuretic peptide receptor-A signaling in unilateral lung ischemia-reperfusion injury in the intact mouse." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 4, pp. L714-23, (2008) (PubMed).

    Uckert, Oelke, Stief, Andersson, Jonas, Hedlund: "Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostate." in: European urology, Vol. 49, Issue 4, pp. 740-5, (2007) (PubMed).

    Ückert, Oelke, Albrecht, Stief, Jonas, Hedlund: "Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minora." in: The journal of sexual medicine, Vol. 4, Issue 3, pp. 602-608, (2007) (PubMed).

    Creighton, Zhu, Alexeyev, Stevens: "Spectrin-anchored phosphodiesterase 4D4 restricts cAMP from disrupting microtubules and inducing endothelial cell gap formation." in: Journal of cell science, Vol. 121, Issue Pt 1, pp. 110-9, (2007) (PubMed).

    Oelke, Hedlund, Albrecht, Ellinghaus, Stief, Jonas, Andersson, Uckert: "Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: immunohistochemical and molecular biology study." in: Urology, Vol. 67, Issue 5, pp. 1111-6, (2006) (PubMed).

    Uckert, Hedlund, Waldkirch, Sohn, Jonas, Andersson, Stief: "Interactions between cGMP- and cAMP-pathways are involved in the regulation of penile smooth muscle tone." in: World journal of urology, Vol. 22, Issue 4, pp. 261-6, (2005) (PubMed).

    Uckert, Oelke, Waldkirch, Stief, Albrecht, Tröger, Jonas, Andersson, Hedlund: "Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves." in: Urology, Vol. 65, Issue 3, pp. 604-10, (2005) (PubMed).

  • 抗原

    PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

    别名

    PDE4

    途径

    cAMP Metabolic Process
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