EPH Receptor A6 抗体 (AA 800-900)
Quick Overview for EPH Receptor A6 抗体 (AA 800-900) (ABIN2746572)
抗原
See all EPH Receptor A6 (Epha6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 800-900
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特异性
- The antibody labels a strong band of EphAR6 at 136 kDa in ABIN1741645 samples and in other cancer cell lines.
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交叉反应
- 小鼠, 大鼠, 猴
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交叉反应 （详细）
- Does not cross react to any other cellular protein.
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产品特性
- EphAR6 selective antibodies were generated against a peptide taken from the human protein. The EphAR6-selective antibodies are affinity purified on an immobilized antigen based affinity matrix, the isolated antibodies were then stabilized in antibody stabilization buffer for long-term storage. The EphAR6- selective antibodies are fully characterized for applications in western blotting and ELISA at the recommended dilutions. The supplier provides EphA6 Western blot positive control samples in ready-to-use SDS-PAGE sample buffer. Limited quantities of antigenic blocking peptide for EphAR6 antibody is also available, please inquire before ordering.
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纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide taken within amino acid region 800-900 on human EphA R6 protein.
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亚型
- IgG
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anti-EPH Receptor A6 (Epha6) antibody
Epha6 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A6 (Epha6) (AA 482-495), (Extracellular) antibodyEpha6 适用: 大鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A6 (Epha6) (AA 132-279) antibodyEpha6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A6 (Epha6) antibodyEpha6 适用: 人, 小鼠, 大鼠 ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A6 (Epha6) (AA 695-795) antibodyEpha6 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3D5B10 unconjugated
anti-EPH Receptor A6 (Epha6) (AA 1006-1035), (C-Term) antibodyEpha6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1637-1638 unconjugated
anti-EPH Receptor A6 (Epha6) (C-Term) antibodyEpha6 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A6 (Epha6) (C-Term) antibodyEpha6 适用: 人, 小鼠, 大鼠 IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A6 (Epha6) antibodyEpha6 适用: 人 WB 宿主: 小鼠 Monoclonal 6C9 unconjugated
anti-EPH Receptor A6 (Epha6) (AA 1-1036) antibodyEpha6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.55-0.75 μg/μL
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注意事项
- Working solutions of antibodies in buffer should be filtered through 0.45 μm filter after every use for long-term storage.
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储存条件
- -20 °C
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储存方法
- For long-term storage of keep at -20 °C. We don't recommend storage of very dilute antibody solutions unless they are prepared in specially formulated multi use antibody dilution buffer.
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- EPH Receptor A6 (Epha6)
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别名
- Eprhin Receptor A6
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背景
- Ephrin A6, a member of the ephrin family, elicits biological responses in retinal neurons. It binds with high affinity to several other EphA receptors and causes growth cone collapse in retinal explants. Ephrin-A6 expression is high at embryonic day 6 (E6) and at embryonic day 8 (E8), when retinal axons grow to their tectal targets, and then this Ephrin-A6 expression gradually declines at later developmental stages. This new ephrin plays a role in the establishment of visual system topography as observed by the asymmetric distribution of ephrin-A6 in retinal cells. High levels of expression of Eph-A6 in the macula of developing human retina showed localization of Eph-A6 to (GC) ganglion cells. Eph receptors and Ephrins have indeed been implicated in multiple aspects of synaptic function, including clustering and modulating N-methyl-D-aspartate receptors, modifying the geometry of postsynaptic terminals, and influencing long-term synaptic plasticity and memory. Eph A6, in line with a number of other Eph receptors and their ephrin ligands, is involved in neural circuits of learning and memory. Genetic inhibition of the ephrin receptor (Eph A6) in knockout mice produced behavioral deficits in tests of learning and memory. The gene for EphAR6 is present on chromosome 3q11.2
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NCBI登录号
- NP_001073917
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UniProt
- B3KS12
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途径
- RTK signaling
抗原
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