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TEK 抗体 (Extracellular Domain)

Name: TEK 抗体 (Extracellular Domain)
Brand: antibodies-online
SKU: ABIN2745570
Availability: OutOfStock

This anti-TEK antibody is a 小鼠单克隆 antibody detecting TEK in WB, ELISA 和 FACS. Suitable for 人.

Immunohistochemistry detection of endogenous TIE-2 in cryo sections of human spleen using anti-TIE-2 (human), mAb (tek2) . (TEK 抗体 (Extracellular Domain))

IHC

1 image

产品编号 ABIN2745570

发货至: 中国

Datasheet as PDF

Quick Overview for TEK 抗体 (Extracellular Domain) (ABIN2745570)

抗原

See all TEK 抗体

TEK (TEK Tyrosine Kinase, Endothelial (TEK))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This TEK antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

Tek2

Discover our top product TEK Primary Antibody

抗原表位
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2

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Extracellular Domain

特异性

Native human TIE-2 in ELISA experiments and on the surface of different human cell types.

交叉反应

人

纯化方法

Protein G purified.

免疫原

Recombinant human soluble extracellular domain of TIE-2.

亚型

IgG1
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 66-185) antibody
TEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A5 unconjugated

anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 571-748) antibody
TEK 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3F5B9 unconjugated

anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 758-789) antibody
TEK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibody
TEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F8 unconjugated

anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 401-550) antibody
TEK 适用: 人, 小鼠, 大鼠, Cow ELISA, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 286-465) antibody
TEK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibody
TEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G6 unconjugated

anti-TEK Tyrosine Kinase, Endothelial (TEK) (C-Term) antibody
TEK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 500-750) antibody
TEK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 758-789), (C-Term) antibody
TEK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01525-01526 unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Lyophilized

溶解方式

Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL.

浓度

Lot specific

缓冲液

Lyophilized.

储存条件

4 °C,-20 °C

储存方法

Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

有效期

6 months
抗原

TEK (TEK Tyrosine Kinase, Endothelial (TEK))

别名

TIE-2

背景

TIE-2 acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. It has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. It is required for normal angiogenesis and heart development during embryogenesis and for post-natal hematopoiesis. After birth, it activates or inhibits angiogenesis, depending on the context. It inhibits angiogenesis and promotes vascular stability in quiescent vessels, where endothelial cells have tight contacts. In migrating endothelial cells that lack cell-cell adhesions, ANGT1 recruits TEK to contacts with the extracellular matrix, leading to the formation of focal adhesion complexes, activation of PTK2/FAK and of the downstream kinases MAPK1/ERK2 and MAPK3/ERK1 and ultimately to the stimulation of sprouting angiogenesis.

UniProt

Q02763

途径

RTK signaling, Growth Factor Binding