Podoplanin 抗体
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北京 101111
Quick Overview for Podoplanin 抗体 (ABIN2745557)
抗原
See all Podoplanin (PDPN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-Podoplanin (mouse), mAb (RTD4E10)
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特异性
- Recognizes mouse podoplanin. Does not cross-react with human podoplanin.
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无交叉反应
- 人
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交叉反应 （详细）
- Does not cross-react with human podoplanin.
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产品特性
- Monoclonal Antibody. Recognizes mouse podoplanin. Does not cross-react with human podoplanin. Isotype: Hamster IgG. Clone: RTD4E10. Applications: ELISA, IHC, IP, WB. Lyophilized. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.
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纯化方法
- Protein G purified.
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免疫原
- Murine thymic stromal cell line.
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亚型
- IgG
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anti-Podoplanin (PDPN) (AA 91-166) antibody
PDPN 适用: 小鼠 WB, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Podoplanin (PDPN) (AA 24-126) antibodyPDPN 适用: 人 IHC, ELISA, IF 宿主: 小鼠 Monoclonal PDPN-1433 unconjugated
anti-Podoplanin (PDPN) (AA 24-172) antibodyPDPN 适用: 小鼠, 大鼠 WB, IHC, FACS, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Podoplanin (PDPN) (AA 23-143) antibodyPDPN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Podoplanin (PDPN) antibodyPDPN 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB1445 unconjugated Recombinant Antibody
anti-Podoplanin (PDPN) antibodyPDPN 适用: 小鼠 WB, FACS, IP, IHC (p) 宿主: 大鼠 Monoclonal 8F11 unconjugated
anti-Podoplanin (PDPN) antibodyPDPN 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Podoplanin (PDPN) (AA 1-100) antibodyPDPN 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal PDPN-4009R unconjugated Recombinant Antibody
anti-Podoplanin (PDPN) antibodyPDPN 适用: 小鼠 WB, IP, IHC (fro) 宿主: Golden Syrian Hamster Monoclonal 811 unconjugated
anti-Podoplanin (PDPN) (AA 97-146) antibodyPDPN 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- Lyophilized.
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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有效期
- 6 months
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- Podoplanin (PDPN)
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别名
- Podoplanin
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背景
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Alternate Names/Synonyms: Glycoprotein 36, PA2.26 Antigen, Aggrus
Product Description: Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.
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途径
- Dicarboxylic Acid Transport
抗原
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