我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

FLIP 抗体 (AA 1-480) (Biotin)

Name: FLIP 抗体 (AA 1-480) (Biotin)
Brand: antibodies-online
SKU: ABIN2745531
Availability: OutOfStock

The 小鼠单克隆 anti-FLIP antibody is suitable to detect FLIP in samples from 人. It has been validated for WB, IHC 和 ICC.

产品编号 ABIN2745531

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FLIP 抗体 (AA 1-480) (Biotin) (ABIN2745531)

抗原

See all FLIP (CFLAR) 抗体

FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This FLIP antibody is conjugated to Biotin

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

NF6

Discover our top product CFLAR Primary Antibody

抗原表位
16

15

15

14

9

8

8

5

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-480

原理

anti-FLIP (human), mAb (NF6) (Biotin)

特异性

Recognizes short (FLIPS) and long (FLIPL) splice variants of human FLIP. This antibody recognizes an epitope in the N-terminal DED region (aa1-194).

产品特性

Monoclonal Antibody. Recognizes short (FLIPS) and long (FLIPL) splice variants of human FLIP. This antibody recognizes an epitope in the N-terminal DED region (aa1-194). Isotype: Mouse IgG1. Clone: NF6. Applications: ICC, IHC, WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.

免疫原

Recombinant human FLIP (aa 1-480).

亚型

IgG1
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 100-251) antibody
CFLAR 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A3D12 unconjugated

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 178-277) antibody
CFLAR 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 191-209) antibody
CFLAR 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 1-250) antibody
CFLAR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 161-480) antibody
CFLAR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 178-277) antibody
CFLAR 适用: 人 WB, IF, IP 宿主: 小鼠 Monoclonal 1G1 unconjugated

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 7-100) antibody
CFLAR 适用: 人 WB, IF (cc), FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 401-480) antibody
CFLAR 适用: 人 WB, IF (cc), IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 145-174) antibody
CFLAR 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18044 unconjugated

anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 1-376) antibody
CFLAR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

In PBS containing 10 % glycerol and 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze/thaw cycles.

储存条件

4 °C,-20 °C

储存方法

+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.

有效期

12 months
抗原

FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

别名

FLIP

背景

Alternate Names/Synonyms: I-FLICE, CLARP, CASPER, Usurpin, CASH, FLAME-1
Product Description: FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.

UniProt

O15519

途径

Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development