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PLGF 抗体 (AA 206-221)

This anti-PLGF antibody is a 兔 多克隆 antibody detecting PLGF in WB. Suitable for 人, Chimpanzee 和 猴.
产品编号 ABIN2743614
发货至: 中国

Quick Overview for PLGF 抗体 (AA 206-221) (ABIN2743614)

抗原

See all PLGF (PGF) 抗体
PLGF (PGF) (Placenta Growth Factor (PGF))

适用

  • 104
  • 37
  • 33
  • 1
人, Chimpanzee, 猴

宿主

  • 107
  • 31
  • 2
  • 1

克隆类型

  • 96
  • 45
多克隆

标记

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  • 1
  • 1
  • 1
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This PLGF antibody is un-conjugated

应用范围

  • 100
  • 53
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  • 18
  • 15
  • 14
  • 14
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  • 9
  • 5
  • 4
  • 3
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  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 206-221

    特异性

    Human PGF / PLGF

    纯化方法

    Immunoaffinity purified

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human PLGF(206-221aa REKMKPERCGDAVPRR). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%), Cat (88%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: WB (0.5 - 1 μg/mL)

    Usage: Placental growth factor(PGF, also known as PLGF) codes for an angiogenic factor expressed in placental tissue that is similar to vascular permeability factor/vascular endothelial growth factor(VPF/VEGF). It is a glycosylated dimeric secreted protein able to stimulate endothelial cell growth in vitro. PGF is located on chromosome 14 and has been conserved in evolution. It belongs to the family of vascular endothelial growth factors(VEGFs) and binds to the flt-1 VEGF receptor. PLGF-2, which is a PLGF isoform, binds neuropilin-1 and 2 in a heparin-dependent manner. PGF regulates inter- and intra molecular cross talk between the VEGF RTKs Flt1 and Flk1 and stimulates the phosphorylation of specific Flt1 tyrosine residues and the expression of distinct downstream target genes. Moreover, it plays an important role in pathological angiogenic events and with exerting its biological activities through binding to VEGFR1.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Sterile distilled water

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
  • 抗原

    PLGF (PGF) (Placenta Growth Factor (PGF))

    别名

    PGF / PLGF

    背景

    Name/Gene ID: PGF
    Family: PDGF

    Synonyms: PGF, D12S1900, PGFL, PlGF-2, Placental growth factor, Placental growth factor-like, PLGF, Placenta growth factor, SHGC-10760

    基因ID

    5228

    途径

    VEGFR1 Specific Signals
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