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PAX6 抗体

PAX6 适用: 人, 小鼠, 大鼠, 小鸡 WB, IF, IHC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal PAX6-496 unconjugated
产品编号 ABIN2743487
发货至: 中国
  • 抗原 See all PAX6 抗体
    PAX6 (Paired Box 6 (PAX6))
    适用
    • 111
    • 71
    • 67
    • 14
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 小鸡
    宿主
    • 94
    • 37
    • 1
    小鼠
    克隆类型
    • 86
    • 45
    单克隆
    标记
    • 67
    • 8
    • 5
    • 5
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    • 3
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    This PAX6 antibody is un-conjugated
    应用范围
    • 95
    • 47
    • 45
    • 40
    • 29
    • 26
    • 14
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    • 12
    • 9
    • 7
    • 5
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Human PAX6
    纯化方法
    Protein G purified
    免疫原
    Recombinant human PAX6 protein.

    Type of Immunogen: Recombinant protein
    克隆位点
    PAX6-496
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PAX6 Primary Antibody
  • 应用备注
    Approved: Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), WB (0.5 - 1 μg/mL)

    Usage: PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain. ELISA: Order BSA-free antibody format for coating.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2°C to 8°C.
  • 抗原
    PAX6 (Paired Box 6 (PAX6))
    别名
    PAX6 (PAX6 产品)
    别名
    pax6 antibody, an2 antibody, mgda antibody, wagr antibody, pax-6 antibody, pax6a antibody, xpax6 antibody, XLPAX6 antibody, MGC52531 antibody, PAX-6 antibody, AN antibody, AN2 antibody, D11S812E antibody, MGDA antibody, WAGR antibody, Pax-6 antibody, pax6b antibody, 1500038E17Rik antibody, AEY11 antibody, Dey antibody, Gsfaey11 antibody, Sey antibody, PAXZF-A antibody, Pax6.1 antibody, cb280 antibody, fc20e07 antibody, pax-a antibody, pax[zf-a] antibody, paxzfa antibody, wu:fc20e07 antibody, zfpax-6a antibody, zfpax-6b antibody, paired box 6 antibody, paired box 6 L homeolog antibody, paired box 6 S homeolog antibody, paired box 6a antibody, PAX6 antibody, pax6 antibody, Pax6 antibody, pax6.L antibody, pax6.S antibody, pax6a antibody
    背景
    Name/Gene ID: PAX6

    Synonyms: PAX6, AN2, D11S812E, MGDA, Oculorhombin, Paired box 6, Paired box homeotic gene-6, AN, Aniridia type II protein, WAGR, Paired box protein Pax-6
    基因ID
    5080
    途径
    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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