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ESR2 抗体 (C-Term)

This anti-ESR2 antibody is a 小鼠 单克隆 antibody detecting ESR2 in WB, ELISA, IHC, IF, FACS, IP 和 IHC (p). Suitable for 人, 小鼠, 大鼠, 绵羊, Pig, 马 和 猴.
产品编号 ABIN2740736
发货至: 中国

Quick Overview for ESR2 抗体 (C-Term) (ABIN2740736)

抗原

See all ESR2 抗体
ESR2 (Estrogen Receptor 2 (ESR2))

适用

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人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This ESR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

ERb455
  • 抗原表位

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    C-Term

    特异性

    Human ESR2 / ER Beta

    纯化方法

    Protein G purified

    免疫原

    The C-terminus fragment of recombinant human Estrogen Receptor beta protein.

    Type of Immunogen: Recombinant protein

    亚型

    IgG2a
  • 应用备注

    Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

    Usage: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including alpha and beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER alpha and beta are differentially activated by various ligands. Ligand interaction triggers a cascade of events, including dissociation from heat shock proteins, recepter dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and beta may be regulated by distinct mechanisms even though they share many functional characteristics. ELISA: Order BSA-free antibody format for coating.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2°C to 8°C.
  • 抗原

    ESR2 (Estrogen Receptor 2 (ESR2))

    别名

    ESR2 / ER beta

    背景

    Name/Gene ID: ESR2
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: ESR2, ESTRB, ER Beta, ERbeta, ER-BETA, ESR-BETA, ESRB, Estrogen receptor 2 (ER beta), NR3A2, Estrogen receptor beta, Estrogen receptor beta 4

    基因ID

    2100

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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