ESR2 抗体 (C-Term)
Quick Overview for ESR2 抗体 (C-Term) (ABIN2740736)
抗原
See all ESR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - C-Term
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特异性
 - Human ESR2 / ER Beta
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纯化方法
 - Protein G purified
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免疫原
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                        The C-terminus fragment of recombinant human Estrogen Receptor beta protein.
Type of Immunogen: Recombinant protein - 
                                            
亚型
 - IgG2a
 
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应用备注
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                        Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)
Usage: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including alpha and beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER alpha and beta are differentially activated by various ligands. Ligand interaction triggers a cascade of events, including dissociation from heat shock proteins, recepter dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and beta may be regulated by distinct mechanisms even though they share many functional characteristics. ELISA: Order BSA-free antibody format for coating. - 
                                            
说明
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Target Species of Antibody: Human
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - Lot specific
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缓冲液
 - PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C
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储存方法
 - Store at 2°C to 8°C.
 
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- ESR2 (Estrogen Receptor 2 (ESR2))
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别名
 - ESR2 / ER beta
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背景
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                        Name/Gene ID: ESR2
Subfamily: NR3 Steroid receptor
Family: NHR
Synonyms: ESR2, ESTRB, ER Beta, ERbeta, ER-BETA, ESR-BETA, ESRB, Estrogen receptor 2 (ER beta), NR3A2, Estrogen receptor beta, Estrogen receptor beta 4 - 
                                            
基因ID
 - 2100
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途径
 - Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
 
抗原
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