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CD74 抗体

This anti-CD74 antibody is a 小鼠 单克隆 antibody detecting CD74 in FACS, WB, IF, IHC, ELISA, IP 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN2739637
发货至: 中国

Quick Overview for CD74 抗体 (ABIN2739637)

抗原

See all CD74 抗体
CD74 (HLA-DR-gamma (CD74))

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD74 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

LN-2
  • 特异性

    Human CD74

    纯化方法

    Protein G purified

    免疫原

    SU-DHL-4 lymphoma cells.

    Type of Immunogen: Cells

    亚型

    IgG1 kappa
  • 应用备注

    Approved: ELISA, Flo (0.5 - 1 μg/10 x106), IF (1 - 2 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.5 - 1 μg/mL)

    Usage: CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. CD74 antibody stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. antibody to CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+). ELISA: Order BSA-free format for coating.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2°C to 8°C.
  • 抗原

    CD74 (HLA-DR-gamma (CD74))

    别名

    CD74 / CLIP

    背景

    Name/Gene ID: CD74

    Synonyms: CD74, CD74 antigen, DHLAG, HLADG, HLA-DR-gamma, Ia-associated invariant chain, p33, MHC HLA-DR gamma chain, Ia-GAMMA

    基因ID

    972

    途径

    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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