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CD3 epsilon 抗体

This 兔 多克隆 antibody specifically detects CD3 epsilon in FACS, WB 和 IP. It exhibits reactivity toward 人, 小鼠, 大鼠, Pig, 猴, Cow, 马, 兔, 绵羊, Hamster 和 Orang-Utan.
产品编号 ABIN2739341
发货至: 中国
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Quick Overview for CD3 epsilon 抗体 (ABIN2739341)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

适用

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人, 小鼠, 大鼠, Pig, 猴, Cow, 马, 兔, 绵羊, Hamster, Orang-Utan

宿主

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克隆类型

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多克隆

标记

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This CD3 epsilon antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)
  • 特异性

    Mouse CD3e.

    纯化方法

    Protein A purified

    免疫原

    Amino acids ERPPPVPNPDYEP (156-168). Percent identity by BLAST analysis: Human, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Rabbit, Pig (100%), Chimpanzee, Gorilla, Ferret, Cat, Chicken, Dog (92%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: Flo (0.5 - 1 μg/10 x106), IP, WB (0.5 - 1 μg/mL)

    Usage: This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28  kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms.

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2°C to 8°C.
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3E

    背景

    Name/Gene ID: CD3E

    Synonyms: CD3E, CD3e antigen, CD3-epsilon, T-cell receptor epsilon chain, TCRE, T-cell receptors epsilon chain, T3E, CD3 Epsilon

    基因ID

    916

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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