CD3 epsilon 抗体
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北京 101111
Quick Overview for CD3 epsilon 抗体 (ABIN2739341)
抗原
See all CD3 epsilon (CD3E) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Mouse CD3e.
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纯化方法
- Protein A purified
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免疫原
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Amino acids ERPPPVPNPDYEP (156-168). Percent identity by BLAST analysis: Human, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Rabbit, Pig (100%), Chimpanzee, Gorilla, Ferret, Cat, Chicken, Dog (92%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
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Approved: Flo (0.5 - 1 μg/10 x106), IP, WB (0.5 - 1 μg/mL)
Usage: This antibody recognizes the epsilon-chain of CD3 (CD3e), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the Tcell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the Tcell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the Tcell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the Tcell surface. CD3 antigen is a highly specific marker for Tcells, and is present in majority of Tcell neoplasms. -
说明
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Target Species of Antibody: Mouse
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2°C to 8°C.
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- CD3 epsilon (CD3E)
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别名
- CD3E
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背景
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Name/Gene ID: CD3E
Synonyms: CD3E, CD3e antigen, CD3-epsilon, T-cell receptor epsilon chain, TCRE, T-cell receptors epsilon chain, T3E, CD3 Epsilon -
基因ID
- 916
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途径
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
抗原
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