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CD34 抗体 (N-Term)

This anti-CD34 antibody is a 小鼠 单克隆 antibody detecting CD34 in FACS, WB, IHC, IF, IHC (p) 和 IP. Suitable for 人, Cynomolgus 和 猕猴.
产品编号 ABIN2739286
发货至: 中国

Quick Overview for CD34 抗体 (N-Term) (ABIN2739286)

抗原

See all CD34 抗体
CD34

适用

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人, Cynomolgus, 猕猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD34 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

克隆位点

QBEnd-10
  • 抗原表位

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    N-Term

    特异性

    Human CD34

    无交叉反应

    牛, 犬, 大鼠, 绵羊

    纯化方法

    Protein G purified

    免疫原

    A detergent solubilized vesicular suspension prepared from human term placenta.

    亚型

    IgG1 kappa
  • 应用备注

    Approved: Flo (0.5 - 1 μg/10 x106), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP, WB (0.25 - 0.5 μg/mL)

    Usage: This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120  kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified into three main categories, class I, class II and class III. This is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. CD34 antibody labels > 85 % of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2°C to 8°C.
  • 抗原

    CD34

    别名

    CD34

    背景

    Name/Gene ID: CD34

    Synonyms: CD34, CD34 Molecule, CD34 antigen

    基因ID

    947
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