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Cyclin D1 抗体 (AA 219-238)

This anti-Cyclin D1 antibody is a 兔 多克隆 antibody detecting Cyclin D1 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2738934
发货至: 中国

Quick Overview for Cyclin D1 抗体 (AA 219-238) (ABIN2738934)

抗原

See all Cyclin D1 (CCND1) 抗体
Cyclin D1 (CCND1)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Cyclin D1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 219-238

    特异性

    Human CCND1 / Cyclin D1

    纯化方法

    Immunoaffinity purified

    免疫原

    Amino acids 219-238 (SPNNFLSCYRTTHFLSRVIK) were used as the immunogen for this Cyclin D1 antibody. This mouse sequence is identical to the related rat sequence, and different from the related human sequence by three amino acids. Percent identity by BLAST analysis: Mouse, Rat (100%), Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey (85%), Orangutan, Galago (80%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: WB (0.5 - 1 μg/mL)

    Usage: D-type cyclins are regarded as essential links between cell environment and the core cell cycle machinery. Cyclin D1, the product of the human gene CCND1, is also known as BCL1. Cyclin D1 expression is regulated by the retinoblastoma protein. Expression of Cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. The CCND1 gene can function as an oncogene.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Sterile distilled water

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
  • 抗原

    Cyclin D1 (CCND1)

    别名

    CCND1 / Cyclin D1

    背景

    Name/Gene ID: CCND1

    Synonyms: CCND1, B-cell lymphoma 1 protein, BCL-1 oncogene, B-cell CLL/lymphoma 1, BCL-1, Cyclin D1, G1/S-specific cyclin-D1, U21B31, PRAD1, BCL1, D11S287E, PRAD1 oncogene

    基因ID

    595

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
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