Cyclin D1 抗体 (AA 219-238)
Quick Overview for Cyclin D1 抗体 (AA 219-238) (ABIN2738934)
抗原
See all Cyclin D1 (CCND1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 219-238
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特异性
- Human CCND1 / Cyclin D1
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纯化方法
- Immunoaffinity purified
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免疫原
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Amino acids 219-238 (SPNNFLSCYRTTHFLSRVIK) were used as the immunogen for this Cyclin D1 antibody. This mouse sequence is identical to the related rat sequence, and different from the related human sequence by three amino acids. Percent identity by BLAST analysis: Mouse, Rat (100%), Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey (85%), Orangutan, Galago (80%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
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Approved: WB (0.5 - 1 μg/mL)
Usage: D-type cyclins are regarded as essential links between cell environment and the core cell cycle machinery. Cyclin D1, the product of the human gene CCND1, is also known as BCL1. Cyclin D1 expression is regulated by the retinoblastoma protein. Expression of Cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. The CCND1 gene can function as an oncogene. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Sterile distilled water
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浓度
- Lot specific
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缓冲液
- Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
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- Cyclin D1 (CCND1)
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别名
- CCND1 / Cyclin D1
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背景
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Name/Gene ID: CCND1
Synonyms: CCND1, B-cell lymphoma 1 protein, BCL-1 oncogene, B-cell CLL/lymphoma 1, BCL-1, Cyclin D1, G1/S-specific cyclin-D1, U21B31, PRAD1, BCL1, D11S287E, PRAD1 oncogene -
基因ID
- 595
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途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling
抗原
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