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TDP1 抗体

The 小鼠 单克隆 anti-TDP1 antibody (Clone 4H1) (ABIN2733391) specifically detects TDP1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN2733391
发货至: 中国
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Quick Overview for TDP1 抗体 (ABIN2733391)

抗原

See all TDP1 抗体
TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

适用

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宿主

  • 34
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小鼠

克隆类型

  • 37
  • 6
单克隆

标记

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This TDP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

4H1
  • 产品特性

    Homo sapiens tyrosyl-DNA phosphodiesterase 1 (TDP1), transcript variant 1

    纯化方法

    Purified from mouse ascites fluids by affinity chromatography

    免疫原

    Full length human recombinant protein of human TDP1(NP_060789) produced in HEK293T cell.

    亚型

    IgG1
  • 应用备注

    WB 1:2000,

    说明

    The concentration of the product may vary between diferrent lots.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5-1.0 mg/mL

    缓冲液

    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

    别名

    TDP1

    背景

    The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.

    分子量

    68.2 kDa

    基因ID

    55775

    NCBI登录号

    NM_018319

    HGNC

    55775
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