GDF15 抗体
Quick Overview for GDF15 抗体 (ABIN2728532)
抗原
See all GDF15 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens peptide deformylase (mitochondrial) (PDF), nuclear gene encoding mitochondrial protein
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human PDF (NP_071736) produced in HEK293T cell.
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亚型
- IgG1
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anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody
Verified GDF15 适用: 人 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79) antibodyGDF15 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 221-308) antibodyGDF15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 30-308) antibodyGDF15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (Biotin)GDF15 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal Biotin
anti-Growth Differentiation Factor 15 (GDF15) (AA 195-308) antibodyGDF15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 16-143) antibodyGDF15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 198-308) antibodyGDF15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (N-Term) antibodyGDF15 适用: 人 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79), (N-Term) antibodyGDF15 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB30209 unconjugated
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应用备注
- WB 1:500, IF 1:100, FLOW 1:100
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- GDF15 (Growth Differentiation Factor 15 (GDF15))
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别名
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背景
- Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.
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分子量
- 19.4 kDa
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基因ID
- 64146
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NCBI登录号
- NM_022341
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HGNC
- 64146
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途径
- SARS-CoV-2 Protein Interactome
抗原
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