PDE4B 抗体
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北京 101111
Quick Overview for PDE4B 抗体 (ABIN2728513)
抗原
See all PDE4B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell.
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亚型
- IgG1
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应用备注
- WB 1:500~2000, IHC 1:150, FLOW 1:100,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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别名
- PDE4B
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背景
- This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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分子量
- 83.2 kDa
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基因ID
- 5142
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NCBI登录号
- NM_002600
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HGNC
- 5142
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
抗原
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