PDE4B 抗体
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北京 101111
Quick Overview for PDE4B 抗体 (ABIN2728510)
抗原
See all PDE4B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell.
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亚型
- IgG1
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anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 500-736) antibody
PDE4B 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (C-Term) antibodyVerified PDE4B 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (Ser119), (Ser133), (Ser190) antibodyPDE4B 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 27-215) antibodyPDE4B 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (C-Term) antibodyPDE4B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 189-217) antibodyPDE4B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB18545 unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (N-Term) antibodyPDE4B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) antibodyPDE4B 适用: 人, 小鼠 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 467-516) antibodyPDE4B 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 62-111) antibodyPDE4B 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, Pig, Bat, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B." in: Nature communications, Vol. 7, pp. 10856, (2016) (PubMed).
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- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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别名
- PDE4B
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背景
- This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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分子量
- 83.2 kDa
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基因ID
- 5142
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NCBI登录号
- NM_002600
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HGNC
- 5142
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
抗原
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