PDE4B 抗体
(1 reference)-
- 抗原 See all PDE4B 抗体
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
-
适用
- 人, 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This PDE4B antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
- 产品特性
- Homo sapiens phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant a
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Full length human recombinant protein of human PDE4B(NP_002591) produced in HEK293T cell.
- 克隆位点
- 1D12
- 亚型
- IgG1
- Top Product
- Discover our top product PDE4B Primary Antibody
-
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 500-736) antibody
PDE4B 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (C-Term) antibodyVerified PDE4B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 27-215) antibodyPDE4B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (C-Term) antibodyPDE4B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 62-111) antibodyPDE4B 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, Pig, Bat, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 467-516) antibodyPDE4B 适用: 人, 大鼠, 豚鼠, 马, Cow, 犬, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) antibodyPDE4B 适用: 人, 小鼠 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) antibodyPDE4B 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 189-217) antibodyPDE4B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB18545 unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) antibodyPDE4B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
- 说明
-
The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
-
-
: "AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B." in: Nature communications, Vol. 7, pp. 10856, (2016) (PubMed).
-
: "AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B." in: Nature communications, Vol. 7, pp. 10856, (2016) (PubMed).
-
- 抗原
- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
- 别名
- PDE4B (PDE4B 产品)
- 背景
- This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- 分子量
- 83.2 kDa
- 基因ID
- 5142
- NCBI登录号
- NM_002600
- HGNC
- 5142
- 途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
-
