电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

KEAP1 抗体

KEAP1 适用: 人, 小鼠 WB, IHC, FACS 宿主: 小鼠 Monoclonal 1B4 unconjugated
产品编号 ABIN2724101
发货至: 中国
  • 抗原 See all KEAP1 抗体
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    适用
    • 89
    • 57
    • 29
    • 20
    • 18
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    人, 小鼠
    宿主
    • 91
    • 7
    • 1
    小鼠
    克隆类型
    • 90
    • 9
    单克隆
    标记
    • 44
    • 10
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This KEAP1 antibody is un-conjugated
    应用范围
    • 86
    • 50
    • 33
    • 26
    • 26
    • 16
    • 10
    • 9
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    产品特性
    Homo sapiens kelch-like ECH-associated protein 1 (KEAP1), transcript variant 1
    纯化方法
    Purified from mouse ascites fluids by affinity chromatography
    免疫原
    Full length human recombinnt protein of human KEAP1(NP_987096) produced in HEK293T cell.
    克隆位点
    1B4
    亚型
    IgG1
    Top Product
    Discover our top product KEAP1 Primary Antibody
  • 应用备注
    WB 1:500~2000, IHC 1:150, FLOW 1:100,
    说明

    The concentration of the product may vary between diferrent lots.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5-1.0 mg/mL
    缓冲液
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Mulvaney, Matson, Siesser, Tamir, Goldfarb, Jacobs, Cloer, Harrison, Vaziri, Cook, Major: "Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate." in: The Journal of biological chemistry, Vol. 291, Issue 45, pp. 23719-23733, (2016) (PubMed).

    Caner, Sen Turk, Baris, Cetin, Tepeli, Hacioglu, Sari, Zencir, Dogu, Bagci, Keskin: "MYD88 Expression and L265P Mutation in Mature B-Cell Non-Hodgkin Lymphomas." in: Genetic testing and molecular biomarkers, Vol. 19, Issue 7, pp. 372-8, (2015) (PubMed).

    Mercado, Kizawa, Ueda, Xiong, Kimura, Moses, Curtis, Ito, Barnes: "Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers." in: PLoS ONE, Vol. 9, Issue 2, pp. e88168, (2014) (PubMed).

    Michaeloudes, Mercado, Clarke, Bhavsar, Adcock, Barnes, Chung: "Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 10, pp. 4913-20, (2014) (PubMed).

    Zhao, Duan, Yuan, Quan, Yang, Xi: "A reusable localized surface plasmon resonance biosensor for quantitative detection of serum squamous cell carcinoma antigen in cervical cancer patients based on silver nanoparticles array." in: International journal of nanomedicine, Vol. 9, pp. 1097-104, (2014) (PubMed).

    Vieceli Dalla Sega, Zambonin, Fiorentini, Rizzo, Caliceti, Landi, Hrelia, Prata: "Specific aquaporins facilitate Nox-produced hydrogen peroxide transport through plasma membrane in leukaemia cells." in: Biochimica et biophysica acta, Vol. 1843, Issue 4, pp. 806-14, (2014) (PubMed).

    Rondini, Fang, Runge-Morris, Kocarek: "Regulation of human cytosolic sulfotransferases 1C2 and 1C3 by nuclear signaling pathways in LS180 colorectal adenocarcinoma cells." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 3, pp. 361-8, (2014) (PubMed).

    Adebiyi, Soni, John, Yang: "Lipid rafts are required for signal transduction by angiotensin II receptor type 1 in neonatal glomerular mesangial cells." in: Experimental cell research, Vol. 324, Issue 1, pp. 92-104, (2014) (PubMed).

    Barnett, Liebl, Seymour, Gillen, Lim, Larock, Davies, Schulz, Nizet, Teasdale, Walker: "The globally disseminated M1T1 clone of group A Streptococcus evades autophagy for intracellular replication." in: Cell host & microbe, Vol. 14, Issue 6, pp. 675-82, (2013) (PubMed).

    Tanaka, Tanaka, Harada, Kohda, Matsumura, Shimamoto, Sawabe, Marunaka, Kuwabara, Takahashi, Ito, Nakahari: "A PKG inhibitor increases Ca(2+)-regulated exocytosis in guinea pig antral mucous cells: cAMP accumulation via PDE2A inhibition." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 304, Issue 9, pp. G773-80, (2013) (PubMed).

    Ramdzan, Polling, Chia, Ng, Ormsby, Croft, Purcell, Bogoyevitch, Ng, Gleeson, Hatters: "Tracking protein aggregation and mislocalization in cells with flow cytometry." in: Nature methods, Vol. 9, Issue 5, pp. 467-70, (2012) (PubMed).

  • 抗原
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    别名
    KEAP1 (KEAP1 产品)
    别名
    INrf2 antibody, KLHL19 antibody, INRF2 antibody, mKIAA0132 antibody, Inrf2 antibody, fb36f11 antibody, keap1 antibody, wu:fb36f11 antibody, KEAP1 antibody, klhl19 antibody, zgc:171654 antibody, kelch like ECH associated protein 1 antibody, kelch-like ECH-associated protein 1 antibody, Kelch-like ECH-associated protein 1 antibody, kelch-like ECH-associated protein 1a antibody, kelch like ECH associated protein 1 L homeolog antibody, kelch-like ECH-associated protein 1b antibody, KEAP1 antibody, Keap1 antibody, keap1a antibody, keap1 antibody, keap1.L antibody, keap1b antibody
    背景
    This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
    分子量
    69.5 kDa
    基因ID
    9817
    NCBI登录号
    NM_203500
    HGNC
    9817
    途径
    Maintenance of Protein Location
You are here:
客服