FLIP 抗体
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北京 101111
Quick Overview for FLIP 抗体 (ABIN272307)
抗原
See all FLIP (CFLAR) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of c-FLIP protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 100-251) antibody
CFLAR 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A3D12 unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 178-277) antibodyCFLAR 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 178-277) antibodyCFLAR 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 1G1 unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 191-209) antibodyCFLAR 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 1-250) antibodyCFLAR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 161-480) antibodyCFLAR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 7-100) antibodyCFLAR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 401-480) antibodyCFLAR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 145-174) antibodyCFLAR 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18044 unconjugated
anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 1-376) antibodyCFLAR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/20000-1/40000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
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别名
- CFLAR / Casper / I-FLICE
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背景
- FLIP (FLICE inhibitory protein) is expressed as both long and short forms and is involved in the regulation of apoptosis. The short form of FLIP contains two death effector domains homologous to the death effector domain of the Fas-associating protein FADD. The long form of FLIP, which shares significant homology with the cysteine protease FLICE, contains an additional caspase-like domain, but lacks a catalytic active site and lacks the residues that form the substrate binding pocket in most caspases. FLIP has been designated by independent groups as Casper, I-FLICE, CLARP, FLAME-1 and MRIT. Although its exact role is still being elucidated, FLIP appears to be an important factor in the regulation of apoptosis downstream of all known death receptors.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
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分子量
- approx. 55 kDa
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基因ID
- 8837
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NCBI登录号
- NP_001120655
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UniProt
- O15519
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途径
- Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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