ERCC4 抗体
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北京 101111
Quick Overview for ERCC4 抗体 (ABIN272306)
抗原
See all ERCC4 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of ERCC4/XPF protein.
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交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) antibody
ERCC4 适用: 人, 小鼠 WB, IF, FACS, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) antibodyERCC4 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 3H10 unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) antibodyERCC4 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 2A1 unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) (AA 656-753) antibodyERCC4 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) (C-Term) antibodyERCC4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) (C-Term) antibodyERCC4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) (AA 600-700) antibodyERCC4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) (C-Term) antibodyERCC4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) antibodyERCC4 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4) (AA 431-480) antibodyERCC4 适用: 人, 大鼠, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/5000approx. 1/10000. Western blot: 1/500approx. 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))
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别名
- ERCC4
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背景
- Xeroderma Pigmentosum (XP) is an autosomal recessive disorder characterized by a genetic predisposition to sunlight-induced skin cancer, and it is commonly due to deficiencies in DNA repair enzymes. The most frequent mutations are found in the XP genes from group A through G and group V, which encode for nucleotide excision repair proteins. XPF, which is also designated ERCC4 or ERCC11, is a 115 kDa protein that associates directly with the excision repair cross-complementing 1 (ERCC1) factor. ERCC-1, a functional homolog of Rad10 in S. cerevisiae, is a component of a structure-specific endonuclease that is responsible for 5' incisions during DNA repair. The ERCC1-XPF endonuclease preferentially cleaves one strand of DNA between duplex and singlestranded regions near borders of the stem-loop structure and, thereby, contributes to the initial steps of the nucleotide excision repair process.Synonyms: DNA excision repair protein ERCC-4, DNA repair endonuclease XPF, DNA repair protein complementing XP-F cells, ERCC-4, ERCC11, XPF, Xeroderma pigmentosum group F-complementing protein
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分子量
- approx. 103 kDa
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基因ID
- 2072
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NCBI登录号
- NP_005227
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UniProt
- Q92889
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途径
- DNA Damage Repair
抗原
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