ESR2 抗体
Quick Overview for ESR2 抗体 (ABIN272305)
抗原
See all ESR2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody detects endogenous levels of ER-beta protein. (region surrounding Glu101)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Estrogen Receptor 2 (ESR2) (C-Term) antibody
ESR2 适用: 人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ERb455 unconjugated
anti-Estrogen Receptor 2 (ESR2) (N-Term) antibodyESR2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (C-Term) antibodyESR2 适用: 人, 小鼠, 大鼠, 绵羊, Pig, 马, 猴 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal ERb455 unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 201-300) antibodyESR2 适用: 人, 小鼠, 大鼠, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 46-530) antibodyESR2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 211-240) antibodyESR2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB41114 unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 417-428) antibodyVerified ESR2 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 22-121) antibodyESR2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Estrogen Receptor 2 (ESR2) (pSer105) antibodyESR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 2 (ESR2) (AA 1-280) antibodyESR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/5000-1/10000. Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ESR2 (Estrogen Receptor 2 (ESR2))
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别名
- Estrogen Receptor beta
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背景
- The discovery of a second estrogen receptor has redefined the estrogen signaling pathway and may have broad implications on estrogen-responsive tissues. The new estrogen receptor, named estrogen receptor-beta (ERβ), is preferentially expressed in the prostate and maintains some characteristics that are different from ERα.2 The rat tissue distribution and/or the relative level of ERα and ERβ expression seems to be quite different, i.e., moderate to high expression in uterus, testis, pituitary, ovary, kidney, epididymis, and adrenal for ERα and prostate, ovary, lung, bladder, brain, bone, uterus, and testis for ERβ. Within the same organ it often appears that the ER subtypes are expressed in different cell types, supporting the hypothesis that the ER's may have different biological functions. The discovery of ERβ suggests the existence of two previously unrecognized pathways of estrogen signaling, via the ERβ subtype in tissues exclusively expressing this subtype and via the formation of heterodimers in tissues expressing both ER subtypes.The existence of two ER subtypes, their differential expression pattern, and different actions on certain response elements could provide explanations for the striking species-, cell-, and promoter-specific actions of estrogens and antiestrogens.3 Both estrogen receptors appear to be involved in a multitude of regulatory events.Synonyms: ER-beta, ESR2, ESTRB, NR3A2, Nuclear receptor subfamily 3 group A member 2
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分子量
- approx. 46, 60 kDa
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基因ID
- 2100
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NCBI登录号
- NP_001035365
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UniProt
- Q92731
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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