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14-3-3 theta 抗体

YWHAQ 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272267
发货至: 中国
  • 抗原 See all 14-3-3 theta (YWHAQ) 抗体
    14-3-3 theta (YWHAQ)
    适用
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    人, 小鼠, 大鼠
    宿主
    • 88
    • 7
    • 2
    • 1
    • 1
    克隆类型
    • 81
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    多克隆
    标记
    • 54
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    This 14-3-3 theta antibody is un-conjugated
    应用范围
    • 67
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    • 27
    • 26
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    • 7
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of 14-3-3 θ protein. (region surrounding Gln67)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product YWHAQ Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    14-3-3 theta (YWHAQ)
    别名
    14-3-3 Protein theta (YWHAQ 产品)
    别名
    14-3-3 antibody, 14-3-3t antibody, 1c5 antibody, hs1 antibody, 1C5 antibody, HS1 antibody, 2700028P07Rik antibody, AA409740 antibody, AU021156 antibody, R74690 antibody, ywhaq antibody, ywhaq2 antibody, wu:fa91b01 antibody, wu:fb02e12 antibody, wu:fb36f06 antibody, wu:fk86h02 antibody, ywhaq1 antibody, ywhaz antibody, zgc:55499 antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a antibody, 14-3-3 protein theta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b antibody, YWHAQ antibody, ywhaq antibody, Ywhaq antibody, ywhaq.S antibody, ywhaqa antibody, ywhaqb antibody
    背景
    14-3-3 proteins regulate many cellular processes relevant to cancer biology,notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activitiesSynonyms: 14-3-3 protein T-cell, 14-3-3 protein tau, Protein HS1, YWHAQ
    分子量
    approx. 28 kDa
    基因ID
    10971
    NCBI登录号
    NP_006817
    UniProt
    P27348
    途径
    Apoptosis, Myometrial Relaxation and Contraction
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