14-3-3 theta 抗体
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Quick Overview for 14-3-3 theta 抗体 (ABIN272267)
抗原
See all 14-3-3 theta (YWHAQ) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of 14-3-3 θ protein. (region surrounding Gln67)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-14-3-3 theta (YWHAQ) (AA 1-245) antibody
YWHAQ 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 theta (YWHAQ) (AA 1-245) antibodyYWHAQ 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 5C4E7 unconjugated
anti-14-3-3 theta (YWHAQ) (AA 1-245) antibodyYWHAQ 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal AT1A1 unconjugated
anti-14-3-3 theta (YWHAQ) (Center) antibodyYWHAQ 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 theta (YWHAQ) antibodyYWHAQ 适用: 人, 小鼠, 大鼠 WB, IF (cc) 宿主: 兔 Monoclonal 5G1 unconjugated
anti-14-3-3 theta (YWHAQ) (N-Term) antibodyYWHAQ 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 犬, 兔, 非洲爪蟾, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 theta (YWHAQ) (C-Term) antibodyYWHAQ 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 犬, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-14-3-3 theta (YWHAQ) antibodyYWHAQ 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-14-3-3 theta (YWHAQ) antibodyYWHAQ 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4250 unconjugated Recombinant Antibody
anti-14-3-3 theta (YWHAQ) (AA 195-245) antibodyYWHAQ 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- 14-3-3 theta (YWHAQ)
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别名
- 14-3-3 Protein theta
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背景
- 14-3-3 proteins regulate many cellular processes relevant to cancer biology,notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activitiesSynonyms: 14-3-3 protein T-cell, 14-3-3 protein tau, Protein HS1, YWHAQ
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分子量
- approx. 28 kDa
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基因ID
- 10971
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NCBI登录号
- NP_006817
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UniProt
- P27348
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途径
- Apoptosis, Myometrial Relaxation and Contraction
抗原
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