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MKNK1 抗体

MKNK1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272252
发货至: 中国
  • 抗原 See all MKNK1 抗体
    MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))
    适用
    • 63
    • 36
    • 30
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 57
    • 9
    克隆类型
    • 58
    • 8
    多克隆
    标记
    • 52
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MKNK1 antibody is un-conjugated
    应用范围
    • 50
    • 46
    • 12
    • 12
    • 9
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Mnk1 protein. (region surrounding Ile136)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product MKNK1 Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))
    别名
    MKNK1 (MKNK1 产品)
    别名
    MNK1 antibody, MKNK1 antibody, zgc:171912 antibody, 2410048M24Rik antibody, Mnk1 antibody, MAPK signal-integrating kinase 1 antibody, mknk1 antibody, mnk1 antibody, MAP kinase interacting serine/threonine kinase 1 antibody, MAP kinase-interacting serine/threonine kinase 1 antibody, MAP kinase interacting serine/threonine kinase 1 S homeolog antibody, MKNK1 antibody, mknk1 antibody, Mknk1 antibody, mknk1.S antibody
    背景
    The MAPKAP kinases (for MAP kinase activated protein kinases) are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. These include the serine/threonine kinases Rsk-1 (also designated MAPKAP kinase-1), Rsk-2 and Rsk-3, which are phosphorylated by ERK1 and ERK2. Similarly p38 phosphorylates and activates the serine/threonine kinases MAPKAP kinase-2 and MAPKAP kinase-3 (also designated 3pK). The serine/threonine kinases Mnk1 and Mnk2 are substrates for both ERK and p38 MAP kinases.Synonyms: MAP kinase-interacting serine/threonine-protein kinase 1, MNK1
    分子量
    approx. 51 kDa
    基因ID
    8569
    NCBI登录号
    NP_001129025
    UniProt
    Q9BUB5
    途径
    MAPK Pathway, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor
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