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ATF6B 抗体

ATF6B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272250
发货至: 中国
  • 抗原 See all ATF6B 抗体
    ATF6B (Activating Transcription Factor 6 beta (ATF6B))
    适用
    • 33
    • 29
    • 9
    • 5
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    • 2
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    • 1
    • 1
    • 1
    宿主
    • 47
    • 1
    克隆类型
    • 47
    • 1
    多克隆
    标记
    • 17
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    • 2
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    • 2
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    • 2
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    • 1
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    This ATF6B antibody is un-conjugated
    应用范围
    • 41
    • 23
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of ATF-6β protein. (region surrounding Ser425)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product ATF6B Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    ATF6B (Activating Transcription Factor 6 beta (ATF6B))
    别名
    ATF6 beta (ATF6B 产品)
    别名
    CREBL1 antibody, CREB-RP antibody, G13 antibody, AA617266 antibody, ATF6beta antibody, Creb-rp antibody, Crebl1 antibody, activating transcription factor 6 beta antibody, cyclic AMP-dependent transcription factor ATF-6 beta antibody, ATF6B antibody, LOC745411 antibody, Atf6b antibody
    背景
    ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6β homodimer or an ATF-6α/β heterodimer. Binding of the ATF-6β homodimer or ATF-6α/β heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription. Human ATF-6β maps to 1q22-q23 gene locus.Synonyms: ATF-6, Activating transcription factor 6 beta, CREBL1, Creb-rp, Cyclic AMP-dependent transcription factor ATF-6 beta, G13, Protein G13, cAMP response element-binding protein-related protein, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1
    分子量
    approx. 76 kDa
    基因ID
    1388
    NCBI登录号
    NP_001129625
    UniProt
    Q99941
    途径
    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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