MAP4K1 抗体
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北京 101111
Quick Overview for MAP4K1 抗体 (ABIN272248)
抗原
See all MAP4K1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of HPK1 protein. (region surrounding Leu397)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (pSer171) antibody
MAP4K1 适用: 人, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (AA 278-377) antibodyMAP4K1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (AA 30-769) antibodyMAP4K1 适用: 人 WB, ELISA, FACS, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (Tyr381) antibodyMAP4K1 适用: 人 WB 宿主: 兔 Polyclonal RB58818 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (N-Term) antibodyVerified MAP4K1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (AA 321-350), (C-Term) antibodyMAP4K1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1208 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (N-Term) antibodyMAP4K1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (AA 231-330) antibodyMAP4K1 适用: 人 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (AA 346-375) antibodyMAP4K1 适用: 人 WB 宿主: 兔 Polyclonal RB11320 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) (AA 278-377) antibodyMAP4K1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))
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别名
- MAP4K1
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背景
- Several mammalian kinases have been identified with sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase STE20. STE20 is involved in relaying signals from G protein coupled receptors to cytosolic MAP kinase cascades, and it lies upstream of a MAP kinase kinase kinase. Mammalian STE20-like kinases include HPK1, KHS, GLK, NIK, YSK1, Krs-1, Krs-2 and GC kinase. HPK1 (hematopoietic progenitor kinase 1), like many other STE20-like kinases, specifically activates the JNK signaling pathway. HPK1 binds to and phosphorylates MEKK, suggesting it plays an important role in regulating the stress responsive JNK/SAPK signaling pathway.Synonyms: HPK1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEKKK 1, Mitogen-activated protein kinase kinase kinase kinase 1
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分子量
- approx. 91 kDa
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基因ID
- 11184
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NCBI登录号
- NP_001036065
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UniProt
- Q92918
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途径
- TCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
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