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Septin 1 抗体

SEPT1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272245
发货至: 中国
  • 抗原 See all Septin 1 (SEPT1) 抗体
    Septin 1 (SEPT1)
    适用
    • 57
    • 33
    • 17
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 52
    • 4
    • 1
    克隆类型
    • 55
    • 2
    多克隆
    标记
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Septin 1 antibody is un-conjugated
    应用范围
    • 50
    • 24
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Septin 1 protein. (region surrounding Asp205)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product SEPT1 Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE!
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    Septin 1 (SEPT1)
    别名
    Septin-1 (SEPT1) (SEPT1 产品)
    别名
    DIFF6 antibody, LARP antibody, PNUTL3 antibody, SEP1 antibody, CG1403 antibody, Diff6 antibody, Dmel\\CG1403 antibody, anon-19Fa antibody, iby antibody, sep1 antibody, tu1 antibody, Pnutl3 antibody, SEPT1 antibody, Septin-1 antibody, septin 1 antibody, Septin 1 antibody, pfam02452; PemK antibody, SEPT1 antibody, Sep1 antibody, Sept1 antibody, sepT1 antibody
    背景
    The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTP-binding protein, is highly expressed in brain and is regulated by protein kinase G in neurons. The human SEPT4 (H5/PNUTL2/CDCrREL-2) gene encodes ARTS (for apoptosis-related protein in the TGFβ signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGFβ or, to a lesser extent, by other apoptotic agents. ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs.Synonyms: DIFF6, LARP, NY-BR-24, PNUTL3, Peanut-like protein 3, Serologically defined breast cancer antigen NY-BR-24
    分子量
    approx. 40 kDa
    基因ID
    1731
    NCBI登录号
    NP_443070
    UniProt
    Q8WYJ6
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