CDK5R1 抗体
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Quick Overview for CDK5R1 抗体 (ABIN272233)
抗原
See all CDK5R1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of p35 protein. (region surrounding Gln31)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 208-307) antibody
CDK5R1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 110-160) antibodyCDK5R1 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (Tyr579) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (N-Term) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (N-Term) antibodyCDK5R1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 99-307) antibodyCDK5R1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 272-301), (C-Term) antibodyCDK5R1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB36667 unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (AA 30-64), (N-Term) antibodyCDK5R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50920 unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) (C-Term) antibodyCDK5R1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1) antibodyCDK5R1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
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别名
- CDK5R1
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背景
- Cyclin dependent kinase-5 (Cdk5), a key regulator of cell cycle progression, was originally isolated on the basis of its structural homology to Cdc2, a wellcharacterized regulator of cell cycle progression. Although Cdk5 is expressed at the highest level in the brain of adult mice, intermediate levels in testis and low or undetectable levels in all other tissues, brain is the only tissue from which Cdk5 can be isolated as an active kinase. These findings may be explained by the cloning and characterization of a Cdk5 regulatory subunit, designated p35. p35 displays a neuronal cell-specific pattern of expression, physically associates with Cdk5 and activates Cdk5 enzymatic activity. p35 is also expressed in many tissues in a truncated form, designated p25.
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分子量
- approx. 38 kDa
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基因ID
- 8851
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NCBI登录号
- NP_003876
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UniProt
- Q15078
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途径
- Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
抗原
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