NCBP1 抗体
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Quick Overview for NCBP1 抗体 (ABIN272218)
抗原
See all NCBP1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of CBP80 protein. (region surrounding Arg5)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (AA 1-790) antibody
NCBP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (AA 647-675), (C-Term) antibodyNCBP1 适用: 人 WB 宿主: 兔 Polyclonal RB41850 unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (AA 2-99) antibodyNCBP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (AA 2-100) antibodyNCBP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibodyNCBP1 适用: 人, Cow, 犬, 兔, Pig, 非洲爪蟾, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- NCBP1 (Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1))
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别名
- NCBP1
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背景
- In eukaryotes, the majority of mRNAs have an m(7)G cap, which is added cotranscriptionally and plays a critical role in many aspects of mRNA metabolism. The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex(CBC). CBC consists of two cap binding proteins CBP20 and CBP80, which mediate the stimulatory functions of the cap in pre-mRNA splicing, 3' end formation and U snRNA export. The genes CBC1 and CBC2 encode CBP80 and CBP20, respectively. CBP80 comprises three domains, each containing a MIF4G domain. CBP20 has an RNAP fold and associates with the second and third domains of CBP80. CBP also plays a role in nonsense-mediated decay(NMD), which eliminates mRNAs, which prematurely terminate translation.CBP80-bound mRNA undergoes a Synonyms: CBP80, NCBP, Nuclear cap-binding protein subunit 1
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分子量
- approx. 88 kDa
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基因ID
- 4686
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NCBI登录号
- NP_002477
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UniProt
- Q09161
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途径
- Ribonucleoprotein Complex Subunit Organization, Photoperiodism, Methionine Biosynthetic Process
抗原
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