Sp3 抗体
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北京 101111
Quick Overview for Sp3 抗体 (ABIN272209)
抗原
See all Sp3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Sp3/4 protein. (region surrounding Gly659)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Sp3 Transcription Factor (Sp3) (AA 240-350) antibody
Sp3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sp3 Transcription Factor (Sp3) (AA 287-336) antibodySp3 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sp3 Transcription Factor (Sp3) (AA 287-430) antibodySp3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E5 unconjugated
anti-Sp3 Transcription Factor (Sp3) (AA 569-599), (C-Term) antibodySp3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sp3 Transcription Factor (Sp3) (Middle Region) antibodySp3 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sp3 Transcription Factor (Sp3) antibodyKD Validated Sp3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sp3 Transcription Factor (Sp3) (C-Term) antibodySp3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sp3 Transcription Factor (Sp3) (AA 301-384) antibodySp3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sp3 Transcription Factor (Sp3) (AA 287-430) antibodySp3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D4 unconjugated
anti-Sp3 Transcription Factor (Sp3) (AA 516-615) antibodySp3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- Sp3 (Sp3 Transcription Factor (Sp3))
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别名
- SP3 / SPR-2
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背景
- The Sp transcription factor family includes Sp1, Sp2, Sp3 (SPR-2) and Sp4(SPR-1). Sp transcription factors share similar structures but do not share similar functions. All four proteins contain a highly conserved DNA-binding domain composed of three zinc fingers at the C-terminus. Sp family members bind the consensus sequence GGGGCGGGGC and other closely related sequences which are known as GC boxes. Sp1, Sp3 and Sp4 share a high affinity for GC boxes while Sp2 does not. Sp2 only weakly binds to GT boxes. Sp1, Sp2 and Sp3 are ubiquitously expressed, while Sp4 is abundantly expressed in brain with limited expression in other tissues. Sp1 and Sp3,but not Sp2 or Sp4, interact with E2, a regulatory element for the β4 subunit of neuronal nicotinic acetylcholine receptors. Sp3 is the only Sp member to inhibit Sp1 and Sp4 mediated transcription. The gene encoding human Sp2 maps to chromosome 17p32.3.Synonyms: Transcription factor Sp3, Transcription factor Sp4
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分子量
- approx. 85 kDa
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基因ID
- 6670
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NCBI登录号
- NP_001017371
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UniProt
- Q02447
抗原
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