NCBP2 抗体
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Quick Overview for NCBP2 抗体 (ABIN272203)
抗原
See all NCBP2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of CBP20 protein. (region surrounding Arg21)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) (AA 1-156) antibody
NCBP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) antibodyNCBP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) (N-Term) antibodyNCBP2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) (AA 106-156) antibodyNCBP2 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) (AA 1-156) antibodyNCBP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) (N-Term) antibodyNCBP2 适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) (N-Term) antibodyNCBP2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) (AA 1-99) antibodyNCBP2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3A12 unconjugated
anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) (N-Term) antibodyNCBP2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Cap Binding Protein Subunit 2 (NCBP2) (AA 106-156) antibodyNCBP2 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- NCBP2 (Nuclear Cap Binding Protein Subunit 2 (NCBP2))
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别名
- NCBP2
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背景
- In eukaryotes, the majority of mRNAs have an m(7)G cap, which is added cotranscriptionally and plays a critical role in many aspects of mRNA metabolism. The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC). CBC consists of two cap binding proteins, CBP20 and CBP80, which mediate the stimulatory functions of the cap in pre-mRNA splicing, 3' end formation and U snRNA export. The genes CBC1 and CBC2 encode CBP80 and CBP20, respectively. CBP80 comprises three domains, each containing a MIF4G domain. CBP20 has an RNAP fold and associates with the second and third domains of CBP80. CBP also plays a role in nonsense-mediated decay (NMD), a process which eliminates mRNAs, and prematurely terminates translation. CBP80-bound mRNA undergoes a pioneer round of translation before CBP80-CBP20 are replaced by eIF4E, and Upf2 and Upf3 proteins.Synonyms: CBP20, Nuclear cap-binding protein subunit 2, PIG55
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分子量
- approx. 18 kDa
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基因ID
- 22916
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NCBI登录号
- NP_001036005
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UniProt
- P52298
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途径
- Ribonucleoprotein Complex Subunit Organization, Methionine Biosynthetic Process
抗原
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