TRAIL 抗体
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北京 101111
Quick Overview for TRAIL 抗体 (ABIN272200)
抗原
See all TRAIL (TNFSF10) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This TRAIL antibody detects endogenous levels of TRAIL protein. (region surrounding Ser63)
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity-Chromatography using epitope-specific immunogen
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应用备注
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ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
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别名
- CD253 / TRAIL
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背景
- Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also referred to as Apo2 ligand, first identified based on its sequence homology to TNF and Fas/Apo ligand is a member of the TNF family of cytokines and either exists as a type II membrane or soluble protein. TRAIL induces apoptosis in a variety of transformed cell lines and plays a role in anti-tumor and anti-viral immune surveillance. TRAIL signals via binding with death receptors DR4 (TRAIL-R1) (4) and DR5 (TRAIL-R2) which can trigger apoptosis as well as NF-κB activation.Synonyms: APO2L, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, TNFSF10, Tumor necrosis factor ligand superfamily member 10
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分子量
- approx. 34 kDa
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基因ID
- 8743
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NCBI登录号
- NP_003801
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UniProt
- P50591
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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