HNF4A 抗体
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Quick Overview for HNF4A 抗体 (ABIN272188)
抗原
See all HNF4A 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of HNF-4α/γ protein. (region surrounding Lys127)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Also reacts to: gamma -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 324-423) antibody
HNF4A 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4E2 unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) antibodyHNF4A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 1-464) antibodyHNF4A 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (pSer313) antibodyHNF4A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) antibodyHNF4A 适用: 小鼠 WB, IHC, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 281-312) antibodyHNF4A 适用: 人, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 1-464) antibodyHNF4A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 200-300) antibodyHNF4A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 281-312) antibodyHNF4A 适用: 人, 大鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB17745 unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) antibodyVerified HNF4A 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))
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别名
- HNF4 alpha / TCF14
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背景
- HNF-1 (α and β), HNF-3 (α, β and γ), HNF-4 (α and γ), and HNF-6 compose, in part, a homoeprotein family designated the Hepatocyte Nuclear Factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. HNF-3α, HNF-3β and HNF-3γ regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3α and HNF-3β have also been shown to be involved in gastrulation events such as body axis formation. HNF-4α and HNF-4γ have been shown to be important for early embryo development. HNF-4α is expressed in liver, kidney, pancreas, small intestine, testis and colon, and HNF-4γ is expressed in each of these tissues except liver. HNF-6 has been shown to bind to the promoter of HNF-3β, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation. Evidence suggests that HNF-6 may also be a transriptional activator for at least 22 other hepatocyte-enriched genes, including cytochrome P450 2C13 and α-1 antitrypsin.Synonyms: HNF4, HNF4A, Hepatocyte nuclear factor 4-alpha, NR2A1, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, Transcription factor HNF-4
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分子量
- approx. 52 kDa
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基因ID
- 3172
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NCBI登录号
- NP_000448
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UniProt
- P41235
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途径
- AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process
抗原
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