FER 抗体
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北京 101111
Quick Overview for FER 抗体 (ABIN272171)
抗原
See all FER 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Fer protein. (region surrounding Asp798)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-FER Tyrosine Kinase (FER) antibody
FER 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 5D2C4 unconjugated
anti-FER Tyrosine Kinase (FER) (AA 782-811), (C-Term) antibodyFER 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB03222 unconjugated
anti-FER Tyrosine Kinase (FER) (AA 1-300) antibodyFER 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 1457CT181-12-17 unconjugated
anti-FER Tyrosine Kinase (FER) antibodyFER 适用: 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal 1487CT794-8-50 unconjugated
anti-FER Tyrosine Kinase (FER) (Ser376) antibodyFER 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) antibodyFER 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (AA 521-536), (Middle Region) antibodyFER 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人, 犬, Cow, Pig WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- FER (FER Tyrosine Kinase (FER))
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别名
- FER / TYK3
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背景
- Fer is a non-receptor protein-tyrosine kinase (nRTK) of the Fes/Fps family, which shares a functional (SH2) domain and is involved in signaling pathways through receptor tyrosine kinases (RTK) and cytokine receptors. The Fes/Fps family is distinct from c-Src, c-Abl and related nRTKs and was originally distinguished as a homolog to retroviral oncoproteins. In vivo, Fer kinaseassembles into homotrimers via conserved coiled-coil domains. The N-terminal coiled-coil domains of Fer can autophosphorylate in trans, thereby regulating their cellular function through differential phosphorylation states. Growth factor exposure can induce tyrosine phosphorylation of Fer and recruitment of Fer to RTK complexes containing p85. Fer is implicated in insulin signaling, cell-cell signaling, human prostatic proliferative diseases, and is involved in the regulation of G1 progression.Synonyms: Proto-oncogene tyrosine-protein kinase FER, Tyrosine kinase 3, c-FER, p94-FER
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分子量
- approx. 95 kDa
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基因ID
- 2241
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NCBI登录号
- NP_005237
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UniProt
- P16591
抗原
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