SIX3 抗体
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Quick Overview for SIX3 抗体 (ABIN272150)
抗原
See all SIX3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Six3/6 protein. (region surrounding Asp228)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Sine Oculis-Related Homeobox 3 (SIX3) (AA 273-332) antibody
SIX3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Sine Oculis-Related Homeobox 3 (SIX3) (AA 273-332) antibodySIX3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D12 unconjugated
anti-Sine Oculis-Related Homeobox 3 (SIX3) (Internal Region) antibodySIX3 适用: 小鼠 WB, ELISA, IHC, IF, FM, DB 宿主: 豚鼠 Polyclonal unconjugated
anti-Sine Oculis-Related Homeobox 3 (SIX3) (Internal Region) antibodySIX3 适用: 小鼠 WB, ELISA, IHC, IF, FM, DB 宿主: 豚鼠 Polyclonal unconjugated
anti-Sine Oculis-Related Homeobox 3 (SIX3) (C-Term) antibodySIX3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sine Oculis-Related Homeobox 3 (SIX3) (AA 1-332) antibodySIX3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sine Oculis-Related Homeobox 3 (SIX3) (C-Term) antibodySIX3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sine Oculis-Related Homeobox 3 (SIX3) (N-Term) antibodySIX3 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sine Oculis-Related Homeobox 3 (SIX3) (Internal Region) antibodySIX3 适用: 小鼠 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated
anti-Sine Oculis-Related Homeobox 3 (SIX3) (Internal Region) antibodySIX3 适用: 小鼠 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- SIX3 (Sine Oculis-Related Homeobox 3 (SIX3))
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别名
- SIX3
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背景
- The SIX proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Two of these family members Six3 and Six6 (also designated Optx2 and Six9) are required for the specification and proliferation of the eye field in vertebrates, and, therefore, are the vertebrate homologues most closely related to the Drosophila sine oculis protein, which has an essential role in controlling compound eye development. Six3 and Six6 expression largely overlap during development of specific tissues, such as retina, hypothalamus, and pituitary. The human Six6 gene maps to chromosome 14q22.3-q23. Haploinsufficiency of Six6 may cause several developmental disorders, including bilateral anophthalmia and pituitary anomalies. The gene encoding the human Six3 protein maps to chromosome 2p21-p22, a region associated with holoprosencephaly type 2 (HPE2). Deletion of Six3 may be associated with HPE2 disorder, a common, severe malformation of the brain that results from incomplete cleavage of the forebrain during early embryogenesis.Synonyms: Homeobox protein SIX3, Sine oculis homeobox homolog 3
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分子量
- approx. 28 kDa
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基因ID
- 6496
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NCBI登录号
- NP_005404
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UniProt
- O95343
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途径
- Protein targeting to Nucleus
抗原
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