FMR1 抗体 (AA 36-279)
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Quick Overview for FMR1 抗体 (AA 36-279) (ABIN2721254)
抗原
See all FMR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 36-279
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产品特性
- Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli.
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亚型
- IgG2b
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应用备注
- WB 1:500~2000, IHC 1:50,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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别名
- FMR1
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背景
- The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
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分子量
- 71 kDa
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基因ID
- 2332
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NCBI登录号
- NM_002024
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HGNC
- 2332
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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