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Aurora A 抗体

This 兔 多克隆 antibody specifically detects Aurora A in WB, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN272125
发货至: 中国
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Quick Overview for Aurora A 抗体 (ABIN272125)

抗原

See all Aurora A (AURKA) 抗体
Aurora A (AURKA) (Aurora Kinase A (AURKA))

适用

  • 132
  • 78
  • 39
  • 21
  • 17
  • 14
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 124
  • 21
  • 1
  • 1

克隆类型

  • 105
  • 41
多克隆

标记

  • 89
  • 9
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aurora A antibody is un-conjugated

应用范围

  • 111
  • 53
  • 41
  • 39
  • 23
  • 22
  • 15
  • 11
  • 10
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of AurA protein. (region surrounding Tyr338)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    Aurora A (AURKA) (Aurora Kinase A (AURKA))

    别名

    Aurora Kinase A

    背景

    Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Synonyms: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6

    分子量

    approx. 46 kDa

    基因ID

    6790

    NCBI登录号

    NP_003591

    UniProt

    O14965

    途径

    Cell Division Cycle, Asymmetric Protein Localization
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