WASP 抗体
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Quick Overview for WASP 抗体 (ABIN272092)
抗原
See all WASP (WAS) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of WASP protein. (region surrounding Glu284)
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交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 57-170) antibody
WAS 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7B10E4 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 39-251) antibodyWAS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (Internal Region) antibodyVerified WAS 适用: 人 ELISA, IHC, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 129-156), (C-Term) antibodyWAS 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (Internal Region) antibodyWAS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 145-265) antibodyWAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 116-144) antibodyWAS 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23643 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 60-250) antibodyWAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 205-234) antibodyWAS 适用: 人 WB 宿主: 兔 Polyclonal RB40707 unconjugated
anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 122-152), (Middle Region) antibodyWAS 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sdium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
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别名
- WAS / IMD2
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背景
- The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome at Xp11.23. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a 53 kDa proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42.Synonyms: WASp, Wiskott-Aldrich syndrome protein
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分子量
- approx. 53 kDa
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基因ID
- 7454
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NCBI登录号
- NP_000368
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UniProt
- P42768
抗原
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