PEA15 抗体
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北京 101111
Quick Overview for PEA15 抗体 (ABIN272058)
抗原
See all PEA15 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of PEA-15 protein. (region surrounding Asp110)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (AA 86-115), (C-Term) antibody
PEA15 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21195 unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (AA 1-130) antibodyPEA15 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (C-Term) antibodyPEA15 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, Hamster, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (Middle Region) antibodyPEA15 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (C-Term) antibodyPEA15 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) antibodyPEA15 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (AA 81-130) antibodyPEA15 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (C-Term) antibodyPEA15 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS, pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))
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别名
- PEA15
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背景
- PEA-15 (phosphoprotein enriched in astrocytes) exists in an non-phosphorylated form (N), and two phosphorylated forms, Pa and Pb. PEA-15 is an endogenous substrate for PKC, which mediates the transition from Pa to Pb. The level of PEA-15 phosphorylation changes upon depolymerization or stabilization of tubulins, indicating that PEA-15 co-localizes with microtubules. The first 80 amino acids of PEA-15 correspond to the death effector domain (DED), which is a domain found in proteins that regulate apoptotic signaling pathways. The DED domain is necessary for PEA-15 to block Ras suppression. Although PEA-15 is predominantly expressed in the central nervous system, low levels of PEA-15 are expressed in liver and kidney, and higher levels in muscle. PEA-15 is also referred to as PED, phosphoprotein enriched in diabetes, for its elevated expression in type 2 diabetic patients.Synonyms: Astrocytic phosphoprotein PEA-15, PED, Phosphoprotein enriched in diabetes
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分子量
- approx. 36 kDa
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基因ID
- 8682
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NCBI登录号
- NP_003759
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UniProt
- Q15121
抗原
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