PEA15 抗体
-
- 抗原 See all PEA15 抗体
- PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PEA15 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of PEA-15 protein. (region surrounding Asp110)
- 交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product PEA15 Primary Antibody
-
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (pSer104) antibody
PEA15 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (AA 86-115), (C-Term) antibodyPEA15 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21195 unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (AA 1-130) antibodyPEA15 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (Ser116) antibodyPEA15 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (C-Term) antibodyPEA15 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, Hamster, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (Middle Region) antibodyPEA15 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (C-Term) antibodyPEA15 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) (AA 81-130) antibodyPEA15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) antibodyPEA15 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS, pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
-
- 抗原
- PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))
- 别名
- PEA15 (PEA15 产品)
- 别名
- HMAT1 antibody, HUMMAT1H antibody, MAT1 antibody, MAT1H antibody, PEA-15 antibody, PED antibody, Pea15a antibody, PEA15 antibody, DKFZp459O1410 antibody, proliferation and apoptosis adaptor protein 15 antibody, phosphoprotein enriched in astrocytes 15 antibody, proliferation and apoptosis adaptor protein 15 L homeolog antibody, Astrocytic phosphoprotein PEA-15 antibody, PEA15 antibody, Pea15 antibody, pea15.L antibody, pea15 antibody
- 背景
- PEA-15 (phosphoprotein enriched in astrocytes) exists in an non-phosphorylated form (N), and two phosphorylated forms, Pa and Pb. PEA-15 is an endogenous substrate for PKC, which mediates the transition from Pa to Pb. The level of PEA-15 phosphorylation changes upon depolymerization or stabilization of tubulins, indicating that PEA-15 co-localizes with microtubules. The first 80 amino acids of PEA-15 correspond to the death effector domain (DED), which is a domain found in proteins that regulate apoptotic signaling pathways. The DED domain is necessary for PEA-15 to block Ras suppression. Although PEA-15 is predominantly expressed in the central nervous system, low levels of PEA-15 are expressed in liver and kidney, and higher levels in muscle. PEA-15 is also referred to as PED, phosphoprotein enriched in diabetes, for its elevated expression in type 2 diabetic patients.Synonyms: Astrocytic phosphoprotein PEA-15, PED, Phosphoprotein enriched in diabetes
- 分子量
- approx. 36 kDa
- 基因ID
- 8682
- NCBI登录号
- NP_003759
- UniProt
- Q15121
-
