PDE4D 抗体
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北京 101111
Quick Overview for PDE4D 抗体 (ABIN272057)
抗原
See all PDE4D 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Thhis antibody detects endogenous levels of PDE4D protein. (region surrounding His47)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (C-Term) antibody
Verified PDE4D 适用: 人 WB, ELISA, IHC, EIA 宿主: 山羊 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 466-709) antibodyPDE4D 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 164-213) antibodyPDE4D 适用: 人, 小鼠, 大鼠, 马, 小鸡, Pig, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (C-Term) antibodyPDE4D 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) antibodyPDE4D 适用: 人, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (C-Term) antibodyPDE4D 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) antibodyPDE4D 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4095 unconjugated Recombinant Antibody
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 401-550) antibodyPDE4D 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 581-809) antibodyPDE4D 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
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别名
- PDE4D
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背景
- Phosphodiesterases (PDE) hydrolyze cAMP to 5'AMP and thus play a critical role in the regulation of intracellular cAMP. Division of the PDE superfamily by sequence homology and enzymatic properties yields 11 PDE families. A unique upstream conserved region (UCR) characterizes the PDE4 family. Four separate genes (A-D) encode the PDE4 enzymes, and alternative splicing generates short or long isoforms of each gene. Long PDE4 isoforms contain both UCR1 and UCR2 while short PDE4 isoforms possess only UCR2. Both UCR domains are necessary for dimerization of PDE4 isoforms. The human PDE4D gene maps to chromosome 5q12. The splice variants include isoforms PDE4D1-6.Synonyms: 5'-cyclic phosphodiesterase 4D, DPDE3, EC=3.1.4.17, PDE43, PDE4D, cAMP-specific 3'
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分子量
- approx. 88 kDa
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基因ID
- 5144
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NCBI登录号
- NP_001098101
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UniProt
- Q08499
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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