-
- 抗原 See all ERCC1 抗体
- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This ERCC1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- 产品特性
- Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1), transcript variant 2
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Full length human recombinant protein of human ERCC1(NP_001974) produced in HEK293T cell.
- 克隆位点
- 5A2
- 亚型
- IgG1
- Top Product
- Discover our top product ERCC1 Primary Antibody
-
-
- 应用备注
- WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
- 说明
-
The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
-
-
Aging asymmetry: systematic survey of changes in age-related biomarkers in the annual fish Nothobranchius guentheri." in: Fish physiology and biochemistry, (2016) (PubMed).
: "
-
Aging asymmetry: systematic survey of changes in age-related biomarkers in the annual fish Nothobranchius guentheri." in: Fish physiology and biochemistry, (2016) (PubMed).
-
- 抗原
- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
- 别名
- ERCC1 (ERCC1 产品)
- 背景
- The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.
- 分子量
- 32.4 kDa
- 基因ID
- 2067
- NCBI登录号
- NM_001983
- HGNC
- 2067
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
-