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MMP10 抗体

MMP10 适用: 人, 小鼠, 大鼠 IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272036
发货至: 中国
  • 抗原 See all MMP10 抗体
    MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))
    适用
    人, 小鼠, 大鼠
    宿主
    • 58
    • 9
    克隆类型
    • 60
    • 7
    多克隆
    标记
    • 35
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP10 antibody is un-conjugated
    应用范围
    • 48
    • 30
    • 28
    • 12
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of MMP-10 protein. (region surrounding Ile387)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product MMP10 Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. IF: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))
    别名
    MMP-10 (MMP10 产品)
    背景
    Proteins of the matrix metalloproteinase (MMP) family are zinc containing proteolytic enzymes involved in the breakdown of the extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They also play an important role in apoptosis, tumor cell growth, invasion, metastasis, as well as in angiogenesis and wound healing. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. Most of the MMP's contain a common domain structure, which include a signal sequence, a propeptide, a catalytic domain and a hemopexin-like (Hpx) domain. MMP10 degrades proteoglycans, gelatins of type I, III, IV, and V, weakly collagens III, IV, and V. and fibronectin. It activates procollagenase. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.Synonyms: MMP10, Matrix metalloproteinase-10, SL-2, STMY2, Stromelysin-2, Transin-2
    分子量
    approx. 54 kDa
    基因ID
    4319
    NCBI登录号
    NP_002416
    UniProt
    P09238
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