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BMX 抗体

The 兔 多克隆 anti-BMX antibody is suitable to detect BMX in samples from 人 和 小鼠. It has been validated for WB, IF 和 IHC (p).
产品编号 ABIN272021
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BMX 抗体 (ABIN272021)

抗原

See all BMX 抗体
BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

适用

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人, 小鼠

宿主

  • 80
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克隆类型

  • 80
  • 3
多克隆

标记

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This BMX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of ETK protein. (region surrounding Lys35)

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    DO NOT FREEZE!

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

    别名

    BMX

    背景

    Etk, also known as BMX, is a member of the Bruton's tyrosine kinase (Btk) family (1). It is expressed in a variety of hematopoietic, epithelial and endothelial cells. Etk, like other Btk family members, contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. It participates in multiple signal transduction pathways (2). Phosphorylation of Tyr566 by Src kinase is required for activation of Etk in vivo (3). In endothelial and epithelial cells, Etk is regulated by FAK through phosphorylation at Tyr40 (4).Synonyms: Bone marrow tyrosine kinase gene in chromosome X protein, Cytoplasmic tyrosine-protein kinase BMX, ETK, Epithelial and endothelial tyrosine kinase, NTK38

    分子量

    approx. 78 kDa

    基因ID

    660

    NCBI登录号

    NP_001712

    UniProt

    P51813
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